Results 31 to 40 of about 971 (184)
Cloning and Overexpression of Strictosidine β-D-Glucosidase Gene Short Sequence from Catharanthus roseus in Escherichia coli [PDF]
Advanced Pharmaceutical Bulletin, 2019 Purpose: Strictosidine-β-D-glucosidase (SGD) is considered as a key enzyme in the production of bisindole alkaloids in Catharanthus roseus. The present study illustrated the production of a short sequence of this enzyme in Escherichia coli without codon ...
Ahmed Saeed Arafa +4 more
doaj +1 more source
Microorganisms, 2019 The antimicrobial activity of the marine bisindole alkaloid 2,2-bis(6-bromo-3-indolyl) ethylamine (1) and related synthetic analogues (compounds 2⁻8) against target microorganisms was investigated by Minimum Inhibitory Concentration (MIC ...
Raffaella Campana +3 more
doaj +1 more source
Biotransformation Of l‐Tryptophan To Produce Arcyriaflavin A With Pseudomonas putida KT2440
ChemBioChem, Volume 24, Issue 23, December 1, 2023., 2023 Arcyriaflavin A was produced in Pseudomonas putida KT2440 using genes from Lentzea aerocolonigenes. Cultivation conditions and supply of the precursor l‐tryptophan were optimized. Genetic engineering of outer membrane vesicle release and cultivation with polyurethane adsorbent resulted in product enrichment in the supernatant.
Nora Lisa Bitzenhofer +3 more
wiley +1 more source
Antemitotic activity of strychnopentamine, a bisindolic alkaloid
Journal of Ethnopharmacology, 1984 Strychnopentamine has been tested for its cytotoxic and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine group increases the antimitotic activity of this type of alkaloids.
Tits, Monique +4 more
openaire +3 more sources
Enantioselective Strategies for The Synthesis of N−N Atropisomers
Angewandte Chemie, Volume 135, Issue 31, August 1, 2023., 2023 Recent advances in the enantioselective synthesis of N−N atropisomers are highlighted and discussed within this Review. In particular, the strategies and breakthroughs to obtain this novel and stimulating atropisomeric architecture are presented while a particular attention is given to mechanistic aspects.
Giovanni Centonze +3 more
wiley +1 more source
Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine
Molecules, 2014 In previous works we showed that oral administration of caulerpine, a bisindole alkaloid isolated from algae of the genus Caulerpa, produced antinociception when assessed in chemical and thermal models of nociception.
Luiz Henrique Agra Cavalcante-Silva +11 more
doaj +1 more source
, 2016 A cytotoxic bisindole alkaloid possessing an unprecedented structure constituted from the union of an eburnan half and a novel vinylquinoline alkaloid has been isolated from Leuconotis griffithii.
Tadahiro Etoh (2196640) +5 more
core +2 more sources
Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings
Molecules, 2018 Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid ...
András Keglevich +8 more
doaj +1 more source
10'-Hydroxyusambarensine, a New Antimalarial Bisindole Alkaloid from the Roots of Strychnos Usambarensis [PDF]
, 1999 peer reviewedReinvestigation of Strychnos usambarensis Gilg resulted in the isolation of a tertiary phenolic bisindole alkaloid, 10'-hydroxyusambarensine (1), which was identified by detailed spectroscopic methods.
Angenot, Luc +7 more
core +1 more source
Molecules, 2007 Dried leaves of Catharanthus roseus were extracted with aqueous acidic 0.1 M solution of HCl. Alkaloid-embonate complexes were obtained as precipitates by treating the extract with an alkaline (NaOH) solution of embonic acid (4,4-methylene-bis-3 ...
Marja-Liisa Riekkola +4 more
doaj +1 more source