Results 41 to 50 of about 971 (184)

Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos Nux-Vomica [PDF]

open access: yes, 1998
peer reviewedThe reinvestigation of Strychnos nux-vomica resulted in the isolation of a colored monoquaternary bisindole alkaloid from the roots. The structure of this new orange substance, strychnochrysine (1), was defined by detailed spectroscopic ...
Angenot, Luc   +7 more
core   +1 more source

Studies of New Indole Alkaloid Coupling Methods for the Synthesis of Haplophytine

open access: yes, 2016
The two novel bisindole alkaloid structures shown can be synthesized in a few steps from the canthiphytine derivative ...
Yuan Tian (225002)   +2 more
core   +5 more sources

FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway

open access: yesFrontiers in Pharmacology, 2022
Non-small cell lung cancer (NSCLC) is one of the most common malignancies in the world. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been used as a first-line treatment for patients harboring with EGFR mutations in ...
Shike Yan   +12 more
doaj   +1 more source

Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack [PDF]

open access: yesJournal of Natural Medicines, 2021
Two new bisindole alkaloids, bisnaecarpamines A (1) and B (2), possessing a vobasine-sarpagine type skeleton were isolated from the bark of Tabernaemontana macrocarpa Jack. Their structures were elucidated by extensive spectroscopic methods and chemical correlation.
Amelia, Puteri   +6 more
openaire   +2 more sources

Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark of Strychnos Guianensis [PDF]

open access: yes, 1999
peer reviewedA reinvestigation of Strychnos guianensis resulted in the isolation of a colored quaternary bisindole alkaloid from the stem bark. The structure of this new substance, guiaflavine (1), was defined by detailed spectroscopic methods and ...
Angenot, Luc   +7 more
core   +1 more source

A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin

open access: yesMolecules, 2013
A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5- (1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl)carbonyl]-1H-pyrrole-3-carboxylates were prepared in excellent yields (82-98%) by one-pot reactions between β-dicarbonyl ...
Gianfranco Favi   +5 more
doaj   +1 more source

Transcriptome analysis of Catharanthus roseus for gene discovery and expression profiling. [PDF]

open access: yesPLoS ONE, 2014
The medicinal plant, Catharanthus roseus, accumulates wide range of terpenoid indole alkaloids, which are well documented therapeutic agents. In this study, deep transcriptome sequencing of C.
Mohit Verma   +4 more
doaj   +1 more source

Spasmolytic Effect of Caulerpine Involves Blockade of Ca2+ Influx on Guinea Pig Ileum

open access: yesMarine Drugs, 2013
In this work, we investigated the spasmolytic effect of caulerpine, a bisindole alkaloid isolated from marine algae of the Caulerpa genus, on guinea pig ileum.
Magna Suzana Alexandre-Moreira   +9 more
doaj   +1 more source

Flabellipparicine, a Flabelliformide-Apparicine-Type Bisindole Alkaloid from Tabernaemontana divaricata [PDF]

open access: yes, 2018
Four new monoterpenoid bisindole alkaloids, flabellipparicine (1), 19,20-dihydrovobparicine (2), 10′-demethoxy-19,20-dihydrovobatensine D (3), and 3′-(2-oxopropyl)ervahanine A (4), and 10 known monoterpenoid indole alkaloids were isolated from the stems ...
Mándi, Attila   +10 more
core   +1 more source

Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola

open access: yesMolecules, 2019
As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge Spongosorites calcicola for chemical study, as fractions of this species displayed interesting cytotoxic bioactivities and ...
Laurence K. Jennings   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy