Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos Nux-Vomica [PDF]
peer reviewedThe reinvestigation of Strychnos nux-vomica resulted in the isolation of a colored monoquaternary bisindole alkaloid from the roots. The structure of this new orange substance, strychnochrysine (1), was defined by detailed spectroscopic ...
Angenot, Luc +7 more
core +1 more source
Studies of New Indole Alkaloid Coupling Methods for the Synthesis of Haplophytine
The two novel bisindole alkaloid structures shown can be synthesized in a few steps from the canthiphytine derivative ...
Yuan Tian (225002) +2 more
core +5 more sources
Non-small cell lung cancer (NSCLC) is one of the most common malignancies in the world. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been used as a first-line treatment for patients harboring with EGFR mutations in ...
Shike Yan +12 more
doaj +1 more source
Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack [PDF]
Two new bisindole alkaloids, bisnaecarpamines A (1) and B (2), possessing a vobasine-sarpagine type skeleton were isolated from the bark of Tabernaemontana macrocarpa Jack. Their structures were elucidated by extensive spectroscopic methods and chemical correlation.
Amelia, Puteri +6 more
openaire +2 more sources
Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark of Strychnos Guianensis [PDF]
peer reviewedA reinvestigation of Strychnos guianensis resulted in the isolation of a colored quaternary bisindole alkaloid from the stem bark. The structure of this new substance, guiaflavine (1), was defined by detailed spectroscopic methods and ...
Angenot, Luc +7 more
core +1 more source
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin
A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5- (1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl)carbonyl]-1H-pyrrole-3-carboxylates were prepared in excellent yields (82-98%) by one-pot reactions between β-dicarbonyl ...
Gianfranco Favi +5 more
doaj +1 more source
Transcriptome analysis of Catharanthus roseus for gene discovery and expression profiling. [PDF]
The medicinal plant, Catharanthus roseus, accumulates wide range of terpenoid indole alkaloids, which are well documented therapeutic agents. In this study, deep transcriptome sequencing of C.
Mohit Verma +4 more
doaj +1 more source
Spasmolytic Effect of Caulerpine Involves Blockade of Ca2+ Influx on Guinea Pig Ileum
In this work, we investigated the spasmolytic effect of caulerpine, a bisindole alkaloid isolated from marine algae of the Caulerpa genus, on guinea pig ileum.
Magna Suzana Alexandre-Moreira +9 more
doaj +1 more source
Flabellipparicine, a Flabelliformide-Apparicine-Type Bisindole Alkaloid from Tabernaemontana divaricata [PDF]
Four new monoterpenoid bisindole alkaloids, flabellipparicine (1), 19,20-dihydrovobparicine (2), 10′-demethoxy-19,20-dihydrovobatensine D (3), and 3′-(2-oxopropyl)ervahanine A (4), and 10 known monoterpenoid indole alkaloids were isolated from the stems ...
Mándi, Attila +10 more
core +1 more source
Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola
As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge Spongosorites calcicola for chemical study, as fractions of this species displayed interesting cytotoxic bioactivities and ...
Laurence K. Jennings +6 more
doaj +1 more source

