Results 61 to 70 of about 971 (184)

1H NMR Spectroscopy and MVA Analysis of Diplodus sargus Eating the Exotic Pest Caulerpa cylindracea

Marine Drugs, 2015
The green alga Caulerpa cylindracea is a non-autochthonous and invasive species that is severely affecting the native communities in the Mediterranean Sea. Recent researches show that the native edible fish Diplodus sargus actively feeds on this alga and
Sandra A. De Pascali, Laura Del Coco, Serena Felline, Ernesto Mollo, Antonio Terlizzi, Francesco P. Fanizzi   +5 more
doaj   +1 more source

Ligand‐Based Pharmacophore Mapping and Virtual Screening for the Search of Biguanide‐Like Molecules With Antidiabetic Potentials Targeting Liver Kinase B1

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Type 2 diabetes mellitus (T2DM) is a state where the body’s glucose metabolism is compromised. AMP‐activated protein kinase, or AMPK, has an important part to play in glucose metabolism, and the liver kinase B1 (LKB1) protein functions as a major upstream kinase for AMPK activation, thereby making it appealing therapeutic targets for treating and ...
Rumman Reza, Md. Nazmus Samdani, Niaz Morshed, Raihana Haque Jebin, Imtiaz Ahmed, Md. Selim Reza, Harleen Khatra   +6 more
wiley   +1 more source

Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity

Malaria Journal, 2018
Background Several species of Aspidosperma plants are referred to as remedies for the treatment of malaria, especially Aspidosperma nitidum. Aspidosperma pyrifolium, also a medicinal plant, is used as a natural anti-inflammatory.
Isabela P. Ceravolo, Carlos L. Zani, Flávio J. B. Figueiredo, Markus Kohlhoff, Antônio E. G. Santana, Antoniana U. Krettli   +5 more
doaj   +1 more source

Arenaria serpyllifolia as a Natural Antiviolaceum Agent: Phytochemical, Biological, and Molecular Approaches

ChemistryOpen, Volume 14, Issue 11, November 2025.
Arenaria serpyllifolia extract exhibits strong antioxidant, antimicrobial, antibiofilm, and antiquorum sensing activities. Key compounds, including levoglucosan and guanosine, show potent CviR receptor binding. Violacein inhibition and molecular dynamics confirm their stability, highlighting their potential as quorum sensing inhibitors and therapeutic ...
Meryem Burcu Külahcı, Betül Aydın, Emine Incilay Torunoğlu, Zekeriya Düzgün, Alper Durmaz, Erdi Can Aytar   +5 more
wiley   +1 more source

A New Indole Alkaloid from Voacanga grandifolia [PDF]

, 2014
A new bisindole alkaloid, voacalgine F (1), has been isolated from the bark of Indonesian Voacanga grandifollia (Miq.) Rolfe.
Osamu Shirota, -, Yusuke Hirasawa, -, Alfarius Eko Nugroho, -, Toshio Kaneda, -, Abdul Rahman, -, Idha Kusumawati, -, Azusa Haseo, -, Noor Cholies Zaini, -, Hiroshi Morita, -   +8 more
core   +1 more source

A pair of novel bisindole alkaloid enantiomers from marine fungus Fusarium sp. XBB-9

, 2019
A preliminary research on the marine fungus Fusarium sp. XBB-9 resulted in a pair of novel bisindole alkaloid enantiomers, (+)- and (–)-fusaspoid A (1a/1b) and 12 diverse compounds.
Wen-Jian Lan (1490500), Run-Zhu Fan (7301195), Sharpkate Shaker (6856040), Hou-Jin Li (1490512)   +3 more
core   +1 more source

Chapter 3 Noniridoid Bisindole Alkaloids

, 1995
This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
openaire   +1 more source

Bisnicalaterine A, a Vobasine−Vobasine Bisindole Alkaloid from Hunteria zeylanica

, 2016
A new bisindole alkaloid, bisnicalaterine A (1), consisting of two vobasine-type skeletons, and 3-epivobasinol (2) and 3-O-methylepivobasinol (3), with vobasine-type skeletons, were isolated from the leaves of Hunteria zeylanica, and their structures ...
A. Hamid A. Hadi (112781), Hiroshi Morita (124362), Yusuke Hirasawa (1562092), Yukihiro Goda (1661827), Alfarius E. Nugroho (2196652), Khalijah Awang (236138), Nobuo Kawahara (1647856)   +6 more
core   +1 more source

From data to discovery: leveraging big data in plant natural products biosynthesis research

The Plant Journal, Volume 122, Issue 6, June 2025.
SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie, Tuan‐Anh Minh Nguyen, Truc Kim, Trinh‐Don Nguyen, Thu‐Thuy T. Dang   +4 more
wiley   +1 more source

First De Novo Synthesis of the Bisindole Alkaloid Vinblastine.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +4 more sources