Results 31 to 40 of about 1,369 (198)

Polymorphism of spironolactone: An unprecedented case of monotropy turning to enantiotropy with a huge difference in the melting temperatures [PDF]

, 2018
Postprint (author's final ...
Barrio Casado, María del, Céolin, René, Lloveras Muntané, Pol Marcel, Rietveld, Ivo B., Tamarit Mur, José Luis   +4 more
core   +4 more sources

Comparison of the Transdermal Bisoprolol Patch with Oral Bisoprolol Fumarate Administration as a Therapeutic Agent for Idiopathic Frequent Premature Ventricular Contractions

International Heart Journal, 2020
The transdermal bisoprolol patch (TB) was designed to maintain a sustained concentration of bisoprolol in plasma by a higher trough concentration than oral bisoporolol (OB). We compared the efficacy between TB and OB in patients with idiopathic premature ventricular contractions (PVCs) while considering their duration of action.A total of 78 patients ...
Masaya, Shinohara, Ryou, Wada, Shintaro, Yao, Kensuke, Yano, Katsuya, Akitsu, Hideki, Koike, Toshio, Kinoshita, Hitomi, Yuzawa, Takeya, Suzuki, Tadashi, Fujino, Takanori, Ikeda   +10 more
openaire   +4 more sources

Process Validation of Bisoprolol Fumarate 3.75 mg Film-coated Tablets

, 2023
The word validation simply means assessment of validity or action of proving effectiveness. Although validation does not in and of itself improve processes, it does ensure that they have been established correctly and are in compliance. Process validation is the process of validating each individual step.
Gona, Pooja, Hitakshi Machhi, Muskanbanu Shaikh, Shahi, Preeti, Saurabhkumar Patel, Parixit Prajapati   +5 more
openaire   +1 more source

Case report: Impact of hyperthyroidism on psychotic symptoms in schizophrenia comorbid with Graves’ disease

Frontiers in Psychiatry, 2023
IntroductionAuditory hallucinations are the most common type of hallucinations observed in schizophrenia; however, visual hallucinations are not uncommon. In Graves’ disease, depression, hypomania, and psychosis can occur.
Yukiyoshi Sumi, Sanae Kawahara, Kumiko Fujii, Mayu Yamaji, Kou Nakajima, Tsubasa Nakamura, Osamu Horikawa, Yukihiro Fujita, Yuji Ozeki   +8 more
doaj   +1 more source

Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment [PDF]

, 2016
Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated.
Agerstrand, Ashton, Boxall, Boxall, Capleton, Carter, Cooper, Crane, Dong, Drillia, Escher, Fick, Franco, Fu, Halling-Sorensen, Hirsch, Kidd, Kim, Kolpin, Kostich, Lahnsteiner, Laville, Monteiro, Niemuth, Ramirez, Roberts, Rocco, Roos, Sanderson, Santos, Schwab, Schwaiger, Sinclair, Triebskorn, Triebskorn, Wang, Webb, Zha   +37 more
core   +1 more source

Impurity profiling of bisoprolol fumarate by liquid chromatography-high-resolution mass spectrometry: A combination of targeted and untargeted approaches using a synthesis reaction matrix and general unknown comparative screening

Journal of Chromatography Open, 2021
Several examples of the emergence of unexpected impurities in medicinal products in the past, e.g. the 2018 valsartan scandal, disclosed the need for sophisticated approaches in impurity profiling.
Jonas Wohlfart, Elisabeth Jäckel, Oliver Scherf-Clavel, Dirk Jung, Martina Kinzig, Fritz Sörgel, Ulrike Holzgrabe   +6 more
doaj   +1 more source

The Influence of Low and Moderate Carotid Stenosis on Neurophysiologic Status of Patients Undergoing on-pump Coronary Artery Bypass Grafting [PDF]

, 2012
Background: Significant (>70%) extracranial stenosis of the internal carotid artery (ICA) is a known risk factor for brain damage in patients with coronary heart disease (CHD) undergoing coronary artery bypass grafting (CABG).
Olga Trubnikova, Irina Tarasova, Olga Barbarash   +2 more
core   +1 more source

Effects of fixed orthodontic appliance with antihypertensive drugs on the body weight of experimental rats

Journal of Baghdad College of Dentistry, 2023
Background: This study aims to investigate the effect of fixed orthodontic appliances and/or antihypertensive drugs on the weight of experimental rats.
Hadeel A Mahdi , Hayder F Saloom , Muhanad A Kashmola   +2 more
doaj   +1 more source

The Maillard reaction of bisoprolol fumarate with various reducing carbohydrates

European Journal of Pharmaceutical Sciences, 2014
HPLC analysis of drug products containing bisoprolol fumarate and lactose revealed the presence of N-formylbisoprolol, which is a final product of the Maillard reaction. Formulations containing secondary amines and reducing carbohydrates are prone to the condensation of amine and carbonyl functional groups and formation of glycosylamines in ...
Mateusz, Szalka, Jacek, Lubczak, Dorota, Naróg, Marek, Laskowski, Krzysztof, Kaczmarski   +4 more
openaire   +2 more sources

An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK [PDF]

, 2016
Background: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use.
Andreasson, Andreasson, Anyanwu, Arcasoy, Avlonitis, Avlonitis, Behrendt, Benden, Bjørk, Boffini, Boffini, Botha, Brazier, Briggs, Brown, Bury, Charmaz, Christie, Couraud, Curtis, Cypel, Cypel, Cypel, Cypel, Cypel, Cypel, De Perrot, Department of Health, Entwistle, Fielding, Fischer, Fisher, Fisher, Fisher, Fisher, Fisher, Fisher, Gibbs, Glaser, Great Britain, Haugh, Henriksen, Information Services Division, Ingemansson, International Society for Heart and Lung Transplantation, ISD Scotland, Itano, Jirsch, Joint Formulary Committee, Kaba, Kaneda, Kierans, Korovesi, Krutsinger, Lee, Littlefield, Long, Lowton, Lowton, Machuca, Martins, Mays, Moran, Naef, National Health Service, National Heart Lung and Blood Institute, National Institute for Health and Care Excellence, National Institute for Health Care Excellence, NHS Blood and Transplant, NHS Blood and Transplant, NHS Business Service Authority, Office for National Statistics, Okada, OPTUM, Orens, O’Grady, RAND Health, RAND Health Corporation, Renshaw, Roberts, Royal College of Surgeons, Sage, Sanchez, Sanchez, Schaeffer, Siebert, Steen, Steen, Taylor, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Tikkanen, TransMedics, TransMedics, UK Government Department of Constitutional Affairs, van Enckevort, Wallinder, Ware, Warnecke, Warnecke, Wierup, World Medical Organization, XVIVO Perfusion, Zych   +102 more
core   +4 more sources