Results 261 to 270 of about 54,594 (319)

A novel bispecific siRNA concept: Efficient dual knockdown of <i>YAP1</i> and <i>WWTR1</i> with a single guide strand. [PDF]

Mol Ther Nucleic Acids
Ueda K, Yamada Y, Tanaka H, Sato T, Sasaki J, Sakamoto S, Minomi K, Yamada H, Sugimoto M.   +8 more
europepmc   +1 more source

Lynozyfic (Linvoseltamab): A First-in-Class Off-the-Shelf T-Cell Redirector for Refractory Multiple Myeloma. [PDF]

EJHaem
Ur Rehman R.
europepmc   +1 more source

Radiologic Pseudoprogression Associated With a Positive Response in a Patient With Multiple Myeloma Treated With a BCMA×CD3 Bispecific Antibody: A Case Report. [PDF]

EJHaem
Khan AM, Kroog GS, Roccia T, Knorr K, Boyapati A, Bumma N.   +5 more
europepmc   +1 more source

Correction: Susilo et al. Whole-Body Physiologically Based Pharmacokinetic Modeling Framework for Tissue Target Engagement of CD3 Bispecific Antibodies. <i>Pharmaceutics</i> 2025, <i>17</i>, 500. [PDF]

Pharmaceutics
Susilo ME, Schaller S, Jiménez-Franco LD, Kulesza A, de Witte WEA, Chen SC, Boswell CA, Mandikian D, Li CC.   +8 more
europepmc   +1 more source

Special Issue: Antibody Therapy for Hematologic Malignancies. [PDF]

Int J Mol Sci
Butchar JP.
europepmc   +1 more source

First case report of immune checkpoint inhibitor-related pneumonitis triggered by bispecific antibody (anti-PD-L1 and anti-CTLA-4) in a patient with non-small cell lung cancer: case report. [PDF]

Transl Lung Cancer Res
Sun H, Liu Y, Chen Z, Fang W, Zhang L, Zhang Y.   +5 more
europepmc   +1 more source

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Engineering bispecific antibodies

Current Opinion in Biotechnology, 1993
Bispecific antibodies have immense potential as reagents and in medicine. Until recently, they were made by combining monoclonal antibodies of two different specificities in vitro, or by fusion of the corresponding hybridomas. Protein engineering now offers the chance to construct a range of small 'designer' bispecific antibodies using antibody ...
P, Holliger, G, Winter
openaire   +2 more sources