Results 261 to 270 of about 1,468,461 (396)

Outcomes in frail patients receiving BCMA-directed bispecific antibodies for relapsed/refractory multiple myeloma. [PDF]

Blood Adv
Adegbite B, Tan CR, Shekarkhand T, Firestone RS, Jurgens EM, Miller K, Lesokhin AM, Shah GL, Korde N, Rajeeve S, Landau HJ, Scordo M, Hassoun H, Maclachlan KH, Shah UA, Hultcrantz M, Hamadeh IS, Derkach A, Nemirovsky D, Giralt SA, Mailankody S, Usmani SZ, Hashmi H.   +22 more
europepmc   +1 more source

Pretargeted radioimmunoscintigraphy in patients with primary colorectal cancer using a bispecific anticarcinoembryonic antigen CEA X anti‐di‐diethylenetriaminepentaacetic acid F(ab′)₂ antibody [PDF]

, 2010
Frits Aarts, Otto C. Boerman, Robert M. Sharkey, Thijs Hendriks, Chien‐Hsing Chang, William J. McBride, Robert P. Bleichrodt, Wim J.G. Oyen, David M. Goldenberg   +8 more
openalex   +1 more source

Vaccination in Multiple Myeloma: Challenges and Strategies

European Journal of Haematology, EarlyView.
ABSTRACT Background Multiple myeloma (MM) is a hematological malignancy characterized by profound immunosuppression resulting from both disease‐related mechanisms and treatment‐induced immune dysfunction. This compromised immune status markedly increases susceptibility to infections, a leading cause of morbidity and mortality in MM patients.
Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Santino Caserta, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Activity of CAR-T cells and bispecific antibodies in multiple myeloma with extramedullary involvement. [PDF]

Blood Cancer J
Steinhardt MJ, Schaefers C, Leypoldt LB, Blau IW, Harzer M, Zhou X, Riedhammer C, Kamili A, Kosch R, Topp LS, Molwitz I, Gross-Fengels NO, Melzer YF, Artzenroth J, Al-Bazaz M, Alsdorf W, Topp MS, Duell J, Mersi J, Waldschmidt J, Bokemeyer C, Einsele H, Kortüm KM, Weisel K, Rasche L.   +24 more
europepmc   +1 more source

A Bispecific Antibody-IFNα2b Immunocytokine Targeting CD20 and HLA-DR Is Highly Toxic to Human Lymphoma and Multiple Myeloma Cells [PDF]

, 2010
Edmund A. Rossi, Diane L. Rossi, Rhona Stein, David M. Goldenberg, Chien‐Hsing Chang   +4 more
openalex   +1 more source

Effectiveness of Octocog Alfa (BAY 81‐8973) to Treat People With Haemophilia A Enrolled in the ATHNdataset, Including Under‐Represented Subgroups

European Journal of Haematology, EarlyView.
ABSTRACT Objectives To evaluate the real‐world effectiveness of octocog alfa (BAY 81‐8973; Kovaltry) in people with haemophilia A (PwHA), including under‐represented subgroups. Methods We retrospectively analysed the American Thrombosis and Hemostasis Network (ATHN) dataset to identify the characteristics, treatment/clinical histories and annualised ...
Martin Chandler, Thomas Moulton, Lena Charafi, Jessica Charlet, Michael Recht   +4 more
wiley   +1 more source

Bispecific antibodies combined with chemotherapy in solid tumor treatment, the path forward? [PDF]

Front Immunol
Yan Y, Yuan J, Peng Y, Zhou C, Liu X, Sun L, Song Q.   +6 more
europepmc   +1 more source

Synthesis and Evaluation of an Anti-MLC1 × Anti-CD90 Bispecific Antibody for Targeting and Retaining Bone-Marrow-Derived Multipotent Stromal Cells in Infarcted Myocardium [PDF]

, 2011
C. William Gundlach, Amy R. Caivano, Maria da Graça Cabreira-Hansen, Amir Gahremanpour, Wells S. Brown, Yi Zheng, Bradley W. McIntyre, James T. Willerson, Richard A. F. Dixon, Emerson C. Perin, Darren G. Woodside   +10 more
openalex   +1 more source

Incremental immunogenicity of multiple doses of SARS‐CoV‐2 vaccination in patients with haematological malignancies

British Journal of Haematology, EarlyView.
Abi Vijenthira, Sita Bhella, Katrina Hueniken, Allison M. Wilkin, Michael Sebag, Peng Wang, Lisa K. Hicks, Annette E. Hay, Sarit Assouline, Amaris Balitsky, Graeme Fraser, Joy Mangel, Carolyn Owen, Anthony Reiman, Laurie Sehn, Heather Sutherland, Corey Arnold, Tamara Leite, Erinn McCarthy, Angela Crawley, Curtis Cooper, Marc‐Andre Langlois, C. Arianne Buchan, VIP Study Investigators   +23 more
wiley   +1 more source

Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application

The FEBS Journal, EarlyView.
Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie, Rebecca Rowan, Dessi Malinova, Lisa Crawford   +3 more
wiley   +1 more source