Results 261 to 270 of about 1,442,988 (353)

BAP1 Loss Affords Lipotoxicity Resistance in Uveal Melanoma

Pigment Cell &Melanoma Research, Volume 38, Issue 3, May 2025.
ABSTRACT Uveal melanoma (UM) is an aggressive intraocular malignancy. Despite effective control of primary tumors, ~50% of UM patients develop metastases, with the liver being the predominant secondary site. BAP1 deficiency, present in ~80% of metastatic UM cases, is strongly associated with increased metastatic risk and poor prognosis.
C. J. Cunanan, A. Amirfallah, A. B. Sanders, K. C. Gallant, M. R. Cavallo, E. A. Homer, O. S. El Naggar, J. K. Farnan, G. Romano, J. L. Hope, J. G. Jackson, E. J. Hartsough   +11 more
wiley   +1 more source

Metabolic Engineering of Glycofusion Bispecific Antibodies for α-Dystroglycanopathies. [PDF]

Antibodies (Basel)
Zhong X, Yan GG, Chaturvedi A, Li X, Gao Y, Girgenrath M, Corcoran CJ, Diblasio-Smith L, LaVallie ER, de Rham T, Zhou J, Abel M, Riegel L, Lim SKH, Bloom L, Lin L, D'Antona AM.   +16 more
europepmc   +1 more source

Bispecific antibodies in immunotherapy for acute leukemia: latest updates from the 66th annual meeting of the American society of hematology, 2024. [PDF]

Front Oncol
Cao W, Ma S, Han L, Xing H, Li Y, Jiang Z, Guo X, Yu J.   +7 more
europepmc   +1 more source

CD20 xCD3 bispecific antibodies for large B cell lymphoma: latest updates from 2024 ASH annual meeting. [PDF]

J Hematol Oncol
Tomarchio V, Rigacci L, Annibali O.
europepmc   +1 more source

Bispecific antibodies in clinical practice: Understanding recent advances and current place in cancer treatment landscape. [PDF]

Clin Exp Med
Verma V, Sharma G.
europepmc   +1 more source

Whole-Body Physiologically Based Pharmacokinetic Modeling Framework for Tissue Target Engagement of CD3 Bispecific Antibodies. [PDF]

Pharmaceutics
Susilo ME, Schaller S, Jiménez-Franco LD, Kulesza A, de Witte WEA, Chen SC, Boswell CA, Mandikian D, Li CC.   +8 more
europepmc   +1 more source

Reprogramming the Tumor Immune Microenvironment with ICAM-1-Targeted Antibody‒Drug Conjugates and B7-H3-CD3 Bispecific Antibodies. [PDF]

Adv Sci (Weinh)
Zhou S, Hong M, Zhao D, Li W, Yuan X, Wang Y, Li H, Yang Y, Jin T, Pan J.   +9 more
europepmc   +1 more source

Retargeting of Human Regulatory T Cells by Single-Chain Bispecific Antibodies

, 2011
Stefanie Koristka, Marc Cartellieri, Anke Theil, Anja Feldmann, Claudia Arndt, Slava Stamova, Irene Michalk, Katrin Töpfer, Achim Temme, Karsten Kretschmer, Martin Bornhäuser, Gerhard Ehninger, Marc Schmitz, Michael Bachmann   +13 more
openalex   +1 more source

Role of Bispecific Antibodies in Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs): Review of Literature. [PDF]

Clin Med Insights Oncol
Mohamed A, Elhawi M, Trybula M, Elshawy M, Chakrabarti S, Selfridge E, Asa SL.   +6 more
europepmc   +1 more source

Selective activation of interleukin-2/interleukin-15 receptor signaling in tumor microenvironment using paired bispecific antibodies. [PDF]

J Immunother Cancer
Montorfani J, Hatterer E, Chatel L, Lesnier A, Viandier A, Daubeuf B, Nouveau L, Malinge P, Calloud S, Masternak K, Ferlin W, Fischer N, Jandus C, Shang L.   +13 more
europepmc   +1 more source