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Bispecific antibodies in oncology
Nature Reviews Drug Discovery, 2022Arman, Esfandiari +2 more
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Bispecific Antibody Therapy in Hemophilia
New England Journal of Medicine, 2017Hemophilia A is the most common severe inherited bleeding disorder in humans. Bleeding occurs as a result of a deficiency or dysfunction of the procoagulant cofactor protein, factor VIII. For the past 50 years, the treatment and prevention of bleeding in hemophilia A has involved the intravenous infusion of plasma-derived or recombinant factor VIII ...
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Bispecific Antibodies for Cancer Therapy
Immunotherapy, 2009Bispecific antibodies, in contrast to conventional monoclonal antibodies, can bind simultaneously two different antigens. Taking advantage of this virtue, they are mostly designed for immune effector cell redirection to tumors and for radionuclide pretargeting to tumors.
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The promise of bispecific antibodies: Clinical applications and challenges
Cancer Treatment Reviews, 2021Sun Min Lim +2 more
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The state of the art of bispecific antibodies for treating human malignancies
EMBO Molecular Medicine, 2021Shuhang Wang, Kun Chen, Qi Lei
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Bioassay Development for Bispecific Antibodies—Challenges and Opportunities
International Journal of Molecular Sciences, 2021Ho Young Lee
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Bispecific antibodies catch cancer neoantigens
Nature Reviews Drug Discovery, 2021openaire +2 more sources