Results 141 to 150 of about 47,580 (341)

CpG-A and B oligodeoxynucleotides enhance the efficacy of antibody therapy by activating different effector cell populations [PDF]

, 2003
Immunostimulatory CpG oligodeoxynucleotides (ODNs) can enhance the therapeutic effect of monoclonal antibodies (mAbs) by enhancing antibody-dependent cell-mediated cytotoxicity (ADCC).
Bakker, A. (Annie), Bevaart, L., Dahle, C.E., Jansen, M.J.H. (Marco), Ojik, H.H. van, Vugt, M.J. van, Weiner, G.J., Winkel, J.G. van de   +7 more
core  

Understanding the structure–property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions [PDF]

, 2023
Bo Zhao, Yunlong Zhao, Stephanie M. Adaniya, Yue Fu, Youmi Moon, Justin Heftel, Shuzhen Chen, Hui Xiao, Ning Li   +8 more
openalex   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Novel bispecific antibody causes tumor regression in patients with non-Hodgkin lymphoma [PDF]

, 2008

openalex   +1 more source

Bispecific antibodies in cancer therapy: Target selection and regulatory requirements

, 2023
Yanze Sun, Xinmiao Yu, Xiao Wang, Kai Yuan, Gefei Wang, Lingrong Hu, Guoyu Zhang, Wenli Pei, Liping Wang, Chengliang Sun, Peng Yang   +10 more
openalex   +1 more source

892 ABL503 (TJ-L14B), PD-L1x4–1BB bispecific antibody induces superior anti-tumor activity by PD-L1-dependent 4–1BB activation with the increase of 4–1BB+CD8+ T cells in tumor microenvironment [PDF]

, 2021
Ui-jung Jung, Jaehyoung Jeon, Shinai Lee, Hyung‐seung Jin, Youngkwang Kim, Eun-Sil Sung, Hyun Joo Kim, Yangmi Lim, Jonghwa Won, Zhengyi Wang, Wenqing Jiang, Jaeho Jung, Gihoon You   +12 more
openalex   +1 more source

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

VIEW, EarlyView.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

Natural Killer Cells in Cancer Immunotherapy [PDF]

, 2019
Arndt MA, Chester C, Cortez VS, D'Andrea A, Elsasser D, Ferrini S, Gao Y, Hartmann F, Lotze MT, Miller JS, Orr MT, Seillet C, Soiffer RJ, Soto EO, Weiner LM, Yron I   +15 more
core   +1 more source

Table_4_A Novel Bispecific Antibody Targeting PD-L1 and VEGF With Combined Anti-Tumor Activities.docx

, 2021
Xiaopei Cui (11781809), Huifeng Jia (11781812), Hong Xin (169242), Lei Zhang (38117), Shi Chen (120917), Simin Xia (2077231), Xue Li (285380), Wei Xu (28953), Xiaofang Chen (256976), Yujie Feng (1362966), Xiaoyue Wei (4787628), Haijia Yu (1510489), Yanting Wang (104823), Yifan Zhan (538015), Xiangyang Zhu (418659), Xuemei Zhang (89768)   +15 more
openalex   +2 more sources

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source