Results 231 to 240 of about 105,923 (295)

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu   +6 more
wiley   +1 more source

Contact Sensitization in Adults With Atopic Dermatitis: A 21‐Year Single‐Center Tertiary Experience

open access: yesContact Dermatitis, Volume 94, Issue 5, Page 465-474, May 2026.
A graphical abstract has been included as supplemental material. ABSTRACT Background Atopic dermatitis is a common chronic inflammatory skin condition. Data on contact sensitization in adults with atopic dermatitis remain limited. Objectives To investigate the prevalence of contact sensitization in adults with and without AD: Patients/Methods A ...
Francesca Caroppo   +5 more
wiley   +1 more source

Intrauterine Exposure to Endocrine-disrupting Chemicals and Risk of Hypospadias: A Pilot Study. [PDF]

open access: yesJ Endocr Soc
Tillotson CV   +8 more
europepmc   +1 more source

Microplastic Impacts on Seafood: A Global Synthesis of Experimental Findings

open access: yesFish and Fisheries, Volume 27, Issue 3, Page 591-606, May 2026.
ABSTRACT Plastic pollution is a growing global concern, with plastic and microplastic particles now widespread in aquatic environments. Microplastics are frequently ingested by marine organisms, including commercially important seafood species. Ingestion can lead to a range of biological effects, influenced by the size, type and quantity of plastic, as
Nina Wootton   +4 more
wiley   +1 more source

Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Here, we show that well studied PET hydrolases can be re‐engineered via directed evolution to deconstruct alternative aromatic‐containing commodity polymers. Introduction of only three mutations into LCCICCG was sufficient to generate an efficient polycarbonate hydrolase with high operational stability that can fully depolymerize a polycarbonate sample
Henry A. Jones   +7 more
wiley   +2 more sources

Paternal sleep deprivation and cardiac dysfunction in offspring: A perspective of myocardial hypertrophy

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2518-2527, 1 May 2026.
Abstract The objective of this work is to assess the effects and potential process of paternal acute sleep deprivation on cardiac function in their offspring. Male and female C57BL/6N mice aged 8–9 weeks (n = 4–5 mice/group) were used. Male mice were selected to construct an acute sleep deprivation model using the modified multiple platform method ...
Yingying Zhang   +12 more
wiley   +1 more source

Comparative Evaluation of Additives in Softwood Fractionation: Impacts on Lignin Recovery and Pulp Quality

open access: yesChemSusChem, Volume 19, Issue 8, 28 April 2026.
Chemical lignin stabilization during acid hydrotropic fractionation is shown to distinctly influence delignification, lignin quality, and pulp performance. Phenol enhances lignin removal, while thiol‐based modifier yields light‐colored lignin, high recovery, and strong pulp.
Juho Antti Sirviö   +7 more
wiley   +1 more source

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