Results 101 to 110 of about 9,802 (262)

Osteonecrosis of the Jaw After Bisphosphonates Treatment in Patients with Multiple Myeloma [PDF]

, 2015
Bone lytic lesion in Multiple myeloma are the most commonly presented symptoms which require treatment with bisphosphonates (BPs). BPs are providing supportive care, reducing the rate of skeletal morbidity but evidently not abolishing it, the criteria ...
Alan Archibald (45342), Aleksei Traspov (4453843), Alex Triantafyllidis (4453852), Bin Yang (103252), Christophe Knorr (4453837), DeodĂĄlia Dias (4453849), Gono Semiadi (2600656), Hendrik-Jan Megens (116285), Kesinee Gatphayak (4453840), Laura Iacolina (3249051), Lawrence Schook (131212), Leilei Cui (416135), Lusheng Huang (110011), Martien Groenen (3191614), Massimo Scandura (534340), Miguel Perez-Enciso (225658), Natalia Zinovieva (4453834), Olivier Hanotte (89422), Panoraia Alexandri (3245007), Pekka Uimari (463592), Peter Dovč (4453846), Richard Crooijmans (512752)   +21 more
core   +3 more sources

Guidelines for the Diagnosis and Treatment of Advanced Breast Cancer in China (2024 Edition)

Cancer Innovation, Volume 4, Issue 6, December 2025.
“The core objective of this guideline is to personalize the management of advanced breast cancer through molecular subtyping, optimizing the balance between survival and quality of life. We integrate recent evidence‐based advances and underscore the essential roles of multidisciplinary collaboration and management of patient‐reported outcomes (PROs ...
Breast Cancer Expert Committee of the National Quality Control Center for Cancer, Breast Cancer Expert Committee of the China Anti‐Cancer Association, Cancer Drug Clinical Research Committee of the China Anti‐Cancer Association   +2 more
wiley   +1 more source

Dental implants in patients treated with oral bisphosphonates. A bibliographic review [PDF]

, 2009
Bisphosphonates inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer.
Calvo Guirado, José Luis, Monpeán Gambín, Mª del Carmen, Montoya Carralero, José Mª, Morata Murcia, Isabel Mª, Parra Mino, Pablo, Ramírez Fernández, Piedad   +5 more
core   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

A 5-year retrospective longitudinal study on the incidence and the risk factors of osteonecrosis of the jaws in patients treated with zoledronic acid for bone metastases from solid tumors [PDF]

, 2017
Background: The aim of this study was to evaluate the incidence and the risk factors of osteonecrosis of the jaw (ONJ) in a group of patients treated with zoledronic acid (ZA) for bone metastases from solid tumors and enrolled in a preventive dental ...
Goldoni, Matteo, Manfredi, Maddalena, Meleti, Marco, Mergoni, Giovanni, Merigo, Elisabetta, Salvagni, Stefania, Vescovi, Paolo   +6 more
core   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

Small Science, Volume 5, Issue 12, December 2025.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li, Xudong Xie, Chong Ding, Shengming Zhang, Liangcong Hu, Bobin Mi, Mengfei Liu, Guohui Liu   +7 more
wiley   +1 more source

Ovariectomy Stimulates and Bisphosphonates Inhibit Intracortical Remodeling in the Mouse Mandible [PDF]

, 2010
Objective –  The pathophysiology of osteonecrosis of the jaw (ONJ) is thought to be linked to suppression of intracortical remodeling. The aim of this study was to determine whether mice, which normally do not undergo appreciable amounts of intracortical
Allen, Matthew R., Burr, David B., Kubek, Daniel J   +2 more
core   +1 more source

Dental Implants in Medically Compromised Patients Undergoing or After Receiving Anti‐Resorptive or Radiotherapy: Retrospective Clinical and Radiographic Data

Clinical Oral Implants Research, Volume 36, Issue 12, Page 1651-1663, December 2025.
ABSTRACT Objective and Aim A retrospective study to evaluate the clinical and radiological outcomes of dental implants placed in compromised patients who have undergone antiresorptive therapy (AR) or head and neck radiotherapy (IR). Material and Methods Dental implant placement was evaluated in compromised patients undergoing or after receiving AR/IR ...
Christian Mertens, Fabian Staudinger, Maximilian Smielowski, Thomas Rückschloss, Gregor Schnug, Jürgen Hoffmann, Oliver Ristow   +6 more
wiley   +1 more source

A retrospective case series on bisphosphonate related osteonecrosis of the jaw in 20 cats

Frontiers in Veterinary Science
IntroductionThis retrospective study highlights the salient aspects of a series of feline patients affected with bisphosphonate related osteonecrosis of the jaw. Though more commonly published in human literature, this presentation is rare in cats.
Suzanna L. Hatunen, Jamie G. Anderson, Cynthia M. Bell, Hugo C. Campos, Matthew D. Finkelman, Bonnie H. Shope   +5 more
doaj   +1 more source

Clinical Experience with Spiramycin in Bisphosphonate-Associated Osteonecrosis of the Jaw

International Journal of Immunopathology and Pharmacology, 2010
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) consists of an exposure of the jaw bone that persists for over 8 weeks in patients with positive history for bisphosphonates. Symptomatology is characterized by dull and ceaseless pain, and in advanced stages, the exposure of necrotic bone is evident, which is frequently associated with purulent ...
Gasparini, Giulio, Saponaro, G, Di Nardo, Francesco, Moro, Alessandro, Boniello, Roberto, Cervelli, Daniele, Marianetti, Tito Matteo, Palazzoni, Giovanni, Pelo, Sandro   +8 more
openaire   +2 more sources