Results 121 to 130 of about 98,296 (378)

Sclerosis of lytic bone metastases after disodium aminohydroxypropylidene bisphosphonate (APD) in patients with breast carcinoma. [PDF]

, 1988
A. Ross Morton, J A Cantrill, G. V. Pillai, A. McMahon, David C. Anderson, Anthony Howell   +5 more
openalex   +1 more source

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. [PDF]

, 2012
Aging reduces the number of mesenchymal stem cells (MSCs) that can differentiate into osteoblasts in the bone marrow, which leads to impairment of osteogenesis.
Guan, Min, Jia, Junjing, Lam, Kit S, Lane, Nancy E, Liu, Ruiwu, Meng, Liping, Nolta, Jan, Panganiban, Brian, Ritchie, Robert O, Shahnazari, Mohammad, Yao, Wei, Zhou, Ping   +11 more
core   +1 more source

Revisiting the Incidence of Hypercalcemia in Contemporary Diagnoses of Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Hypercalcemia is rarely observed in pediatric patients with cancer. However, rare cases of renal insufficiency and osteoporosis have been reported as severe consequences. Published literature focuses predominantly on hypercalcemia in pediatric hematologic malignancies, precluding causative associations with solid tumor disease ...
Felicia Y. Ho, Dajana Alku, Chalinee Monsereenusorn, Nan Chen, Wendy B. London, Allison F. O'Neill   +5 more
wiley   +1 more source

Bisphosphonates: Mechanisms of Action [PDF]

Endocrine Reviews, 1998
The geminal bisphosphonates are a class of drug, developed in the last 30 years, characterised by a P-C-P bond. Consequently, they are analogues of pyrophosphate but are resistant to chemical and enzymatic hydrolysis. The bisphosphonates bind strongly to hydroxyapatite crystals and inhibit their formation and dissolution. This physicochemical effect on
openaire   +5 more sources

Salvianolic Acid A Mitigates Osteoporotic Bone Loss by Repressing Reactive Oxygen Species via the Nrf2–HO‐1 Pathway

Phytotherapy Research, EarlyView.
ABSTRACT Osteoporosis, characterized by osteoclastic bone resorption, has been the focus of research. Studies implicate that reactive oxygen species (ROS) accumulate intracellularly during osteoclastogenesis. Salvianolic acid A (SAA), a compound derived from Salvia miltiorrhiza, has been widely used to treat cardiovascular and cerebrovascular disorders,
Hao Qiu, Chenhui Cai, Ying Zhang, Sizhen Yang, Xu Hu, Tongwei Chu   +5 more
wiley   +1 more source

Spectrum of activity and mechanisms of azole–bisphosphonate synergy in pathogenic Candida

Microbiology Spectrum
Candidiasis places a significant burden on human health and can range from common superficial vulvovaginal and oral infections to invasive diseases with high mortality.
Aidan Kane, Hue Dinh, Leona Campbell, Amy K. Cain, David Hibbs, Dee Carter   +5 more
doaj   +1 more source

Successful control of recurrent angiosarcoma in the external auditory canal with CyberKnife radiosurgery and bisphosphonate risedronate sodium

Dermatologica Sinica, 2015
Angiosarcoma (AS) is a highly aggressive vascular tumor that spreads widely throughout the skin. Since AS tends to recur locally and metastasize early, an additional intensive therapy is necessary.
Eimei Iwama, Taku Fujimura, Akira Hashimoto, Yukikazu Numata, Takahiro Haga, Setsuya Aiba   +5 more
doaj   +1 more source

Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. [PDF]

, 1993
Mohan Singh Sahni, Harald L. Guenther, H. Fleisch, Pascal Collin, T. John Martin   +4 more
openalex   +1 more source

Phillygenin Improves the Focal Adhesion Kinase/Glycogen Synthase Kinase 3β/β‐Catenin Axis to Promote Mesenchymal Stem Cell Osteogenic Differentiation

Phytotherapy Research, EarlyView.
Schematic diagram of Phillygenin improves the focal adhesion kinase/glycogen synthase kinase 3β/β‐catenin axis to promote mesenchymal stem cell osteogenic differentiation. ABSTRACT Forsythiae Fructus, a traditional herb known for its anti‐inflammatory and antioxidant properties, has demonstrated inconclusive effects on bone metabolism in prior studies.
Yuchao Yang, Haidong Zhou, Yining Wang, Ming Yin, Fengying Gong, Shutong Wu, Zhiyin Luo, Zhenyu Bi, Jiahou Xu, Yongfu Chen, Konghe Hu, Jun Ouyang, Jiajun Tang   +12 more
wiley   +1 more source

Prosthodontic care and management of patients with MRONJ from different microbiological backgrounds

Fogorvosi Szemle
Medication-related osteonecrosis of the Jaw (MRONJ) is a severe condition of multifactorial origin, with its exact etiological factors still not fully understood.
Flóra Alíz Lakatos, László Kádár, Péter Schmidt, János König, Andrea Bródy, Károly Frigyes Mensch   +5 more
doaj   +1 more source