Results 211 to 220 of about 67,212 (289)

ROMosozumab early experience in female patients with severe osteoporosis in an Italian real-world setting, the ROMEO study. [PDF]

Osteoporos Int
Adami G, Bartezaghi M, Montanari F, Piccinelli A, Pollastri F, Mastropaolo F, Giorgio F, Benini C, Fassio A, Rossini M, Gatti D, Fornari R, Viapiana O.   +12 more
europepmc   +1 more source

Extracellular Vesicles in Osteoarthritis: From Pathogenic Mediators to Engineered Therapeutics in a Precision Medicine Roadmap

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach, Van Giang Bui, Thanh Liem Nguyen   +2 more
wiley   +1 more source

Teriparatide in Two Patients With Mucopolysaccharidosis Type IVB

JIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT Mucopolysaccharidosis Type IV is a multisystem lysosomal storage disease characterized by severe skeletal dysplasia resulting from impaired degradation of the glycosaminoglycans keratan sulfate and chondroitin‐6‐sulfate. The condition is classified into Types A and B based on the underlying enzyme deficiency.
Mark Wijnen, Evert F. S. van Velsen, J. Gert‐Jan Milhous, Esmee Oussoren, Bram C. J. van der Eerden, Margreet A. E. M. Wagenmakers   +5 more
wiley   +1 more source

Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability. [PDF]

J Pain Res
van der Spek DPC, Huygen FJPM, Hoeks SE, van Daele PLA, Dirckx M.   +4 more
europepmc   +1 more source

Egg yolk hydrolysate shows moderate impact on osteoporosis in ovariectomized rats

Journal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4218-4227, May 2026.
Abstract BACKGROUND This study investigated the protective effect of egg yolk hydrolysate (FC) on osteoporosis in ovariectomized (OVX) rats, a well‐established model of postmenopausal bone loss. OVX rats were fed diets supplemented with 0.2% or 1% FC for 13 weeks.
Ilekuttige Priyan Shanura Fernando, Da Shi, Zihan Wang, Michael Doschak, Jianping Wu   +4 more
wiley   +1 more source

Impact of Prolonged Bisphosphonate Therapy on Atypical Femoral Fractures: Insights from a Single-Center Experience. [PDF]

J Pers Med
Caldaci A, Panebianco P, Condorelli S, Zappalà N, Costarella L, Sapienza M, Testa G, Pavone V.   +7 more
europepmc   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Comparative efficacy and safety of anti-osteoporotic therapies for kidney transplant recipients: a systematic review and network meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Liu X, Li X, Zhao Y, Gao Q, Xue Y, Wu Z, Shi X, Wu X.   +7 more
europepmc   +1 more source

Pathways to enhancing prenatal diagnosis of skeletal dysplasias

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Skeletal dysplasias are a group of Mendelian disorders that variably alter the development of the musculoskeletal system and phenotypically range from mild short stature syndromes to severe perinatal or neonatal morbidity. Prenatal diagnosis of these conditions can be challenging due to the lack of precision with ultrasound imaging compared to
Michelle Joy Wang, Christina Jacobsen, Jennifer Arnold, Ronald J. Wapner, Deborah Krakow   +4 more
wiley   +1 more source

Potent Competitive Inhibitors of Ecto-5'-nucleotidase (CD73) based on 6‑(Het)aryl-7-deazapurine Ribonucleoside 5'‑<i>O</i>‑Bisphosphonates. [PDF]

ACS Pharmacol Transl Sci
Šinkevičiu̅tė U, Šímová M, Staník R, Poštová Slavětínská L, Blažková K, Šácha P, Lepšík M, Řezáč J, Konvalinka J, Ormsby T, Tichý M, Hocek M.   +11 more
europepmc   +1 more source