Results 231 to 240 of about 67,212 (289)

Pre-Operative Bone Health in Elective Spine Surgery, From Risk Assessment to Optimization Strategies: A Narrative Review. [PDF]

Global Spine J
Ng MK, Hitchner M, Dalton J, Lee Y, Green WA, Baek G, Mathew J, Eichbaum YK, Hilibrand AS, Vaccaro AR, Schroeder GD, Kepler CK.   +11 more
europepmc   +1 more source

A phase 1 study of ASTX727 plus talazoparib in patients with triple‐negative or hormone resistant/HER2‐negative metastatic breast cancer

Cancer, Volume 132, Issue 8, 15 April 2026.
Abstract Background Poly(adenosine diphosphate ribose) polymerase (PARP) is recruited to DNA damage sites along with epigenetic factors such as DNA methyltransferase 1 (DNMT1). Inhibitors of DNMT modulate reactive oxygen species (ROS)‐cyclic adenosine monophosphate (cAMP)/Protein Kinase A signaling and induce a “BRCAness phenotype” that further ...
Kathy D. Miller, Alexandra Thomas, Sandra Althouse, Yong Zang, Erin Conder, Ryan Burgos, Bryan P. Schneider, Tarah Ballinger, Emily Douglas, Katherine Ansley, H. Josh Jang, Woonbok Chung, Jean‐Pierre Issa, Kenneth P. Nephew, Feyruz V. Rassool   +14 more
wiley   +1 more source

Double-edged-sword effect of bisphosphonates on the osteogenic differentiation of human periodontal ligament stem cells. [PDF]

Front Pharmacol
Li M, Wang J, Ruan H, Wang Z, Wang S, He Y, Zhang Z.   +6 more
europepmc   +1 more source

Nitroxide‐Mediated Polymerization Synthesis of Geminal Bisphosphonate‐Functionalized (Co)polymers and Their Affinity to Hydroxyapatite Surface

Journal of Polymer Science, Volume 64, Issue 8, Page 1692-1703, 15 April 2026.
A novel styrenic monomer bearing gem‐bisphosphonate groups is synthesized in a single step. The nitroxide‐mediated (co)polymerization of this monomer proceeds in a well‐controlled manner, yielding bisphosphonate‐functionalized (co)polymers with low dispersity.
Hien The Ho, Nam Hoai Nguyen, Marion Rollet, Didier Gigmes, Trang N. T. Phan   +4 more
wiley   +1 more source

Modern Strategies for Osteoporosis Therapy: Current Status and Prospects for Targeted Intervention. [PDF]

Int J Mol Sci
Omelchenko V, Koval V, Slazhneva N, Bondarenko N, Shatunova E, Vorobyeva M, Korolev M.   +6 more
europepmc   +1 more source

Bisphosphonates use is associated with increased coronary artery calcification in the general population: The Rotterdam study. [PDF]

Atheroscler Plus
Shahraki MN, Chaker L, van Velsen E, van Overbruggen M, Heugens C, Kavousi M, Stricker BH, Bos D.   +7 more
europepmc   +1 more source

Postmenopausal Osteoporosis: From Molecular Pathways to Therapeutic Targets-A Mechanism-to-Practice Framework Integrating Pharmacotherapy, Fall Prevention, and Adherence into Patient-Centered Care. [PDF]

J Clin Med
Ena G, Soyfoo M.
europepmc   +1 more source

Perioperative disease activity and metabolic optimization in spinal Paget's disease. [PDF]

Brain Spine
Abudayeh A, Fishchenko I.
europepmc   +1 more source

Health and adverse events associated with extended oral bisphosphonates among postmenopausal women: a systematic review.

J Clin Endocrinol Metab
Oka P, Moosa AS, Koh EYL, Ng CJ.
europepmc   +1 more source

The Conundrum of Medical Fracture Prevention in Chronic Kidney Disease-Summary of the Evidence and Pragmatic Clinical Guidance. [PDF]

J Clin Med
Schietzel S, Huynh-Do U.
europepmc   +1 more source