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Cost-Effectiveness of Biosimilar Denosumab Versus Bisphosphonates in Postmenopausal Osteoporosis. [PDF]
Flanigan J +8 more
europepmc +1 more source
Longitudinal osteoporosis therapy: treat-to-target and sequential strategies-a narrative review. [PDF]
Tskhakaia I, Danila MI.
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Bisphosphonate-induced Esophagitis Dissecans Superficialis: A Rare Case Report. [PDF]
Bade Y, Ahmed J, Bharti V.
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Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion. [PDF]
Baroncelli GI +21 more
europepmc +1 more source
Abstract: Bisphosphonates belong to a class of compounds similar to pyrophosphate. In these compounds the oxygen atom of the pyrophosphate is replaced by a carbon atom resulting in a P‐C‐P bond. They exert a potent inhibitory effect on osteoclasts and are therefore potent antiresorptive agents. They reduce bone turnover, increase bone mineral density,
Robert Graham Goodwin Russell +1 more
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Bisphosphonates and Bisphosphonate Induced Osteonecrosis
Oral and Maxillofacial Surgery Clinics of North America, 2007Bisphosphonate-induced osteonecrosis of the jaws is the correct term for this real drug complication that most dental practitioners face. All nitrogen-containing bisphosphonates pose a risk, which is related to the route of administration, the potency of the bisphosphonate, and the duration of use.
Yoh, Sawatari, Robert E, Marx
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Bisphosphonates and Osteoporosis
New England Journal of Medicine, 2002Osteoporosis affects millions of postmenopausal women in the United States alone. For white women who reach 50 years of age, the lifetime risk of vertebral fracture is about one in three, and that for hip fracture is one in six. One tenth to one fifth of the women who have a hip fracture die within a year after it occurs, and one quarter must move ...
openaire +4 more sources
Pharmacology of bisphosphonates
Bone, 2011Four decades of preclinical and clinical research of the pharmacology of bisphosphonates have generated data and concepts that have considerably improved their clinical use. However, despite this progress several pharmacological aspects relevant to bisphosphonate action on bone are still incompletely understood.
Serge Cremers, Socrates E Papapoulos
exaly +4 more sources
Bone, 2011
Bone metastases result in considerable morbidity, often affecting quality of life and independence over years, and may place complex demands on health care resources. The bisphosphonates have been shown to reduce skeletal morbidity in multiple myeloma and solid tumours affecting bone by 30-50%.
Robert E, Coleman, Eugene V, McCloskey
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Bone metastases result in considerable morbidity, often affecting quality of life and independence over years, and may place complex demands on health care resources. The bisphosphonates have been shown to reduce skeletal morbidity in multiple myeloma and solid tumours affecting bone by 30-50%.
Robert E, Coleman, Eugene V, McCloskey
openaire +2 more sources

