Results 161 to 170 of about 61,588 (194)

BK Polyomavirus-Associated Urothelial Carcinoma of the Bladder with a Background of BK Polyomavirus Nephropathy in a Kidney Transplant Recipient

Nephron, 2023
Renal transplant recipients are at increased risk for the development of a malignant neoplasm. Polyomavirus-associated urothelial carcinoma is a rare tumor that occurs in renal transplant recipients, with approximately 41 cases reported since 2002.
Sari Iwasaki, Kenta Takahashi, H. Katano, Tadaki Suzuki, H. Sasaki, H. Harada, Y. Takada, Keishi Makita, Y. Fukasawa, Takahiro Tsuji   +9 more
semanticscholar   +1 more source

Polyomavirus BK

The Lancet Infectious Diseases, 2003
Polyomavirus hominis 1, better known as BK virus (BKV), infects up to 90% of the general population. However, significant clinical manifestations are rare and limited to individuals with impaired immune functions. BKV has been associated with diverse entities such as haemorrhagic cystitis, ureteric stenosis, vasculopathy, pneumonitis, encephalitis ...
Hans H, Hirsch, Jürg, Steiger
openaire   +2 more sources

Polyomavirus BK infection

Transplantation Proceedings, 2003
Because it is an important factor affecting renal transplant function, BK infections are significant problem in posttransplant. BK nephropathy develops in 5% of renal allograft recipients, in most cases within the first year after the procedure. The gold standard for BK nephropathy diagnosis is still immunohistochemical staining for large T antigen in ...
B, Matłosz, A, Mróz, M, Durlik, A, Wesołowska, A, Sadowska, T, Cieciura, A, Perkowska, D, Deborska-Materkowska, J, Szmidt, G, Michalak, L, Paczek, M, Lao   +11 more
openaire   +2 more sources

The effect of BK polyomavirus large T antigen on CD4 and CD8 T cells in kidney transplant recipients.

Transplant Immunology, 2022
Human BK polyomavirus (BKPyV) can affect the machinery of the host cell to induce optimal viral replication or transform them into tumor cells. Reactivation of BKPyV happens due to immunosuppression therapies following renal transplantation which might ...
Maryam Rahim Foroudi, R. Yaghobi, A. Afshari, J. Roozbeh, S. Miresmaeili, Amaneh Javid   +5 more
semanticscholar   +1 more source

BK polyomavirus in solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

Clinical Transplantation, 2019
The present AST‐IDCOP guidelines update information on BK polyomavirus (BKPyV) infection, replication, and disease, which impact kidney transplantation (KT), but rarely non‐kidney solid organ transplantation (SOT).
H. Hirsch, P. Randhawa
semanticscholar   +1 more source

Impact of BK Polyomavirus Plasma Viral Load in Kidney Transplant Outcomes.

Transplantation Proceedings, 2022
BACKGROUND BK polyomavirus infection (BKVi) is an important cause of kidney transplant (KT) loss, but there is scarce evidence on the impact of BK plasma viral load on graft function and long-term KT survival.
M. Alonso, F. Villanego, C. Orellana, L. A. Vigara, N. Montiel, A. Aguilera, J. Amaro, T. García, A. Mazuecos   +8 more
semanticscholar   +1 more source

Leflunomide for Polyomavirus Type BK Nephropathy

New England Journal of Medicine, 2005
To the Editor: Polyomavirus type BK nephropathy is an aggressively destructive disease occurring in up to 8 percent of patients with renal allografts,1,2 with rates of graft loss within one year of 30 to 65 percent.3,4 There is no therapy with proven efficacy.
James W, Williams, Basit, Javaid, Predeep V, Kadambi, Daniel, Gillen, Robert, Harland, J Richard, Thistlewaite, Marc, Garfinkel, Preston, Foster, Walter, Atwood, J Michael, Millis, Shane M, Meehan, Michelle A, Josephson   +11 more
openaire   +2 more sources

Update on human polyomavirus BK nephropathy

Diagnostic Cytopathology, 2009
AbstractPolyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus‐associated nephropathy, a major cause of renal allograft failure. Although BKV‐associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developing in 45% of affected ...
David, Cimbaluk, Lisa, Pitelka, Larry, Kluskens, Paolo, Gattuso   +3 more
openaire   +2 more sources

Transplacental transmission of human polyomavirus BK

Journal of Medical Virology, 1998
The presence of BK virus (BKV) and JC virus (JCV) in autopsy materials (placenta, brain, and kidney) of aborted fetuses was investigated by PCR using two sets of primers, specific for the regulatory region (RR) and for the capsid protein VP1, respectively.
PIETROPAOLO, Valeria Antonietta, DI TARANTO C., DEGENER, Anna Marta, JIN L., SINIBALDI, Laura, BAIOCCHINI A., MELIS, Marco, ORSI, Nicola   +7 more
openaire   +3 more sources

Polyomavirus BK-Specific Immunity after Kidney Transplantation

Transplantation, 2004
Failure to mount or maintain a protective immune response may influence the development of polyomavirus BK (BKV)-associated nephropathy (PVAN). However, limited data are so far available on BKV-specific immunity after kidney transplantation. BKV-specific cellular immune response was retrospectively analyzed in kidney recipients with or without BKV ...
COMOLI P, AZZI, ALBERTA, MACCARIO R, BASSO S, BOTTI G, BASILE G, FONTANA I, LABIRIO M, COMETA A, POLI F, PERFUMO F, LOCATELLI F, GINEVRI F.   +12 more
openaire   +4 more sources