Results 141 to 150 of about 28,332 (270)

Glomerular plasmalemma vesicle‐associated protein‐1 as an endothelial remodelling marker complementing C4d in chronic active antibody‐mediated rejection

open access: yesHistopathology, EarlyView.
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi   +7 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil   +3 more
wiley   +1 more source

Feasibility and outcomes of kidney transplantation in patients with end‐stage kidney disease after haemopoietic stem cell transplantation

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Advances in haemopoietic stem cell transplantation (HSCT) have improved long‐term survival, but they have also led to late complications, such as nephropathy. However, the safety and feasibility of kidney transplantation (KT) in patients with HSCT‐related end‐stage kidney disease (ESKD) remain unclear.
Bioh Kim   +6 more
wiley   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

BK virus infection, replication, and diseases in pediatric kidney transplantation [PDF]

open access: yes, 2018
Polyomavirus-associated nephropathy is diagnosed in 2-8% of pediatric renal transplants and often precedes renal allograft dysfunction. Without intervention, however, significant graft dysfunction is observed in more than 50% of cases, although ...
Hirsch, Hans, Acott, Philip
core  

Sea Lice (Lepeophtheirus salmonis) Harbour Putative Fish Pathogens: Insights From Illumina and Nanopore Sequencing

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Ectoparasites that penetrate host skin can act as biological or mechanical vectors for pathogens and, in some cases, serve as reservoirs. Crustacean ectoparasites of fish are potential vectors of pathogens, which is especially relevant for obligate pathogens (e.g., Aeromonas salmonicida) with limited seawater survival. Sea lice (Lepeophtheirus
B. Klimesova   +9 more
wiley   +1 more source

Assessing the Reduction of Recurrent Admissions Using OM‐85 for the Treatment of Preschool Wheeze (ARROW): Protocol for a Multi‐Centre, Randomised, Double‐Blind, Placebo‐Controlled Trial

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims Acute wheezing illnesses are among the most common reasons preschool‐aged children are admitted to hospital. Readmission rates are high, and novel preventive strategies are required. OM‐85 is an orally administered bacterial lysate that stimulates anti‐viral immune responses and reduces excessive airway inflammation associated with ...
Jessica C. Costa‐Pinto   +114 more
wiley   +1 more source

Oxidative stress in honey bees (Apis mellifera) and small carpenter bees (Ceratina calcarata) across different landscapes

open access: yesPhysiological Entomology, EarlyView.
First comparative study in oxidative stress between wild bees and managed bees. Bees collected from organic landscapes exhibited the lowest OX levels. Pesticide profiles were different among landscapes. Abstract Oxidative stress (OX) is a state of imbalance between antioxidants and reactive oxygen species, which are the byproducts of oxidative ...
Keiana Briscoe   +5 more
wiley   +1 more source

Kit for diagnosis of BK virus infection by the real-time Polymerase Chain Reaction method (PCR)

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The presented work comprises information about developed by Republic Scientific and Practical Center for Epidemiology and Microbiology the diagnostic kit for detection the BK virus DNA in clinical samples by the real-time Polymerase Chain Reaction method.
K. L. Dziadziulia   +5 more
doaj  

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