Results 31 to 40 of about 24,998 (232)

BK Virus Nephropathy Revisited [PDF]

open access: yesAmerican Journal of Transplantation, 2017
More than 20 years after its first description and increased morbidity under powerful immunosuppression, the understanding of the pathogenesis of BK polyomavirus induced allograft nephropathy (BKVN) has changed clinical practice in renal transplantation.
openaire   +2 more sources

BK Virus in Kidney Transplant Recipients: The Influence of Immunosuppression

open access: yesJournal of Transplantation, 2011
The incidence of BK virus infection in kidney transplant recipients has increased over recent decades, coincident with the use of more potent immunosuppression.
Katherine A. Barraclough   +3 more
doaj   +1 more source

Transformation of Human Embryonic Fibroblasts by BK Virus, BK Virus DNA and a Subgenomic BK Virus DNA Fragment

open access: yesJournal of General Virology, 1982
Human embryonic fibroblasts (HEF) have been transformed by BK virus (BKV) DNA and by u.v.-inactivated or live BKV alone or in association with methyl-cholanthrene (MTC). The transformed cells produced BKV large T and small t antigens as well as the cellular 53 kdal protein, detected by immunofluorescence and immunoprecipitation.
GROSSI, Maria Pia   +8 more
openaire   +4 more sources

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

open access: yesFrontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser   +3 more
doaj   +1 more source

Longitudinal viral kinetic study of BK virus in renal transplant patients - A single-center study in Sri Lanka

open access: yesJournal of Clinical Virology Plus, 2022
Background: There is a strong association between high-level BK viraemia and the development of BK virus-associated nephropathy. Therefore, understanding the kinetics of BK virus replication following transplantation would be helpful in predicting high ...
K.D.S.T. Abeywardana   +4 more
doaj   +1 more source

Prevalence of anti-BK polyomavirus IgG in A Sample of Iraqi renal transplant recipients

open access: yesDiyala Journal of Medicine, 2022
Background: BK virus, a human polyomavirus, causes nephropathy and allograft loss in renal transplant recipients. Although it was discovered in 1971, understanding of the humoral immune response to BKV is limited.
Ghufran Hammoodi Abed ,   +5 more
doaj   +1 more source

P1649IS BK VIRUS CARCINOGENIC?! [PDF]

open access: yesNephrology Dialysis Transplantation, 2020
Abstract Background and Aims The role of polyomaviruses (PyV) in malignancy is controversial, this can be demonstrated in three ways; Firstly, hit and run mechanism where polyomaviruses contribute to the early phases of oncogenic progression.
Ahmed Halawa, Ahmed Saleh
openaire   +1 more source

BK polyomavirus associated progressive multifocal leukoencephalopathy in a person living with HIV

open access: yesBrain, Behavior, & Immunity - Health, 2021
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the white matter central nervous system occurring in immunocompromised patients particularly those with T cell deficiency such as in HIV, haematological and solid organ ...
Brendan O'Kelly   +5 more
doaj   +1 more source

Molecular Networks Involved in the Immune Control of BK Polyomavirus

open access: yesClinical and Developmental Immunology, 2012
BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. BK virus reactivates in 30%–80% of kidney transplant recipients resulting in BK virus-related nephropathy in 1%–10% of cases.
Eva Girmanova   +6 more
doaj   +1 more source

BK Virus-Associated Nephropathy without Viremia in an Adolescent Kidney Transplant Recipient

open access: yesSiriraj Medical Journal, 2017
BK virus can reactivate in kidney transplant recipients leading to BK virus-associated nephropathy (BKVAN) and allograft dysfunction. Pathogenesis begins with viral replication, follows by viruria, viremia and nephropathy.
Kraisoon Lomjansook, M.D.   +4 more
doaj   +3 more sources

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