Results 81 to 90 of about 7,824 (162)

The Genomic Characterization of KPC-Producing Klebsiella pneumoniae from the ICU of a Teaching Hospital in Shanghai, China

Infection and Drug Resistance, 2022
Yingying Du,1,* Shikui Mu,1,* Yan Liu,2 Yinghua Yuan,2 Yunlou Zhu,2 Lijie Ma,2 Qixing Wang,2 Zhengfang Zhu,2 Yuhao Liu,1 Sheng Wang1 1Department of Critical Care Medicine, Shanghai Tenth People’s Hospital, Tongji University, School of Medicine ...
Du Y, Mu S, Liu Y, Yuan Y, Zhu Y, Ma L, Wang Q, Zhu Z, Liu Y, Wang S   +9 more
doaj  

Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant Klebsiella pneumoniae (CRKP) Infections

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Carbapenem‐resistant Klebsiella pneumoniae (CRKP) has become a global public health threat, with significantly increased morbidity and mortality among high‐risk inpatients. High‐risk genotypes of CRKP, primarily including K. pneumoniae carbapenemase (KPC), oxacillinase‐48–like (OXA‐48–like), New Delhi metallo‐β‐lactamase (NDM), imipenemase ...
Qiongfang Zhang, Ze Fang, Bo Fang, Hailing Zeng, Jiaojiao Xu, Muhammad Abu Bakr Shabbir   +5 more
wiley   +1 more source

Food Animals and Retail Meat as Emerging Source of Beta‐Lactamase Gene Carrying Virulent Non–baumannii Acinetobacter spp. in Meghalaya, India

International Journal of Food Science, Volume 2026, Issue 1, 2026.
Non–baumannii Acinetobacter (NBA) are increasingly recognized as reservoirs of antimicrobial resistance genes (ARGs) along the food chain, although data from livestock and meat remain scarce, particularly for blaNDM‐positive isolates. In this study, 450 samples were collected in Meghalaya, India, including cattle and pig rectal swabs, chicken meat, and
Madesh Angappan, Sandeep Ghatak, Dadimi Bhargavi, A. Arun Prince Milton, Kandhan Srinivas, Samir Das, A. Sen, Vanita Lyngdoh, Muhammad Asif Zahoor   +8 more
wiley   +1 more source

Insights of β‐Lactams Resistance in Klebsiella pneumoniae Clinical Isolates: A Focus on Molecular Identification of Drug Resistance

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is associated with high antimicrobial resistance and is commonly isolated from colonization and healthcare‐associated infections (HAIs). This study is aimed at developing and validating molecular assays to detect resistance genes belonging to the bla family in resistant K. pneumoniae isolates.
Lavouisier F. B. Nogueira, Marília S. Maia, Marco A. F. Clementino, Ila F. N. Lima, Jorge L. N. Rodrigues, Luciana V. C. Fragoso, Glairta S. Costa, Jose Q. S. Filho, Alexandre Havt, Deiziane V. S. Costa, Lyvia M. V. C. Magalhães, Dilza Silva, José K. Sousa, Aldo A. M. Lima, Divakar Sharma   +14 more
wiley   +1 more source

KPC-2 allelic variants in Klebsiella pneumoniae isolates resistant to ceftazidime-avibactam from Argentina: blaKPC-80, blaKPC-81, blaKPC-96 and blaKPC-97

Microbiology Spectrum
Ceftazidime-avibactam (CZA) therapy has significantly improved survival rates for patients infected by carbapenem-resistant bacteria, including KPC producers. However, resistance to CZA is a growing concern, attributed to multiple mechanisms.
María Belén Sanz, Fernando Pasteran, Juan Manuel de Mendieta, Florencia Brunetti, Ezequiel Albornoz, Melina Rapoport, Celeste Lucero, Laura Errecalde, Maria Rosa Nuñez, Renata Monge, Magdalena Pennini, Pablo Power, Alejandra Corso, Sonia A. Gomez   +13 more
doaj   +1 more source

IS26-mediated cointegration generates a plasmid co-harbouring blaIMP-4 and blaKPC-2 in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance
This study aims to explore the phenotypic and genotypic characteristics of a plasmid that co-harbours blaIMP-4 and blaKPC-2 in a carbapenem-resistant Klebsiella pneumoniae.Strain K194 was isolated from a 60-year-old patient. Species identification was performed with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, followed ...
Jiawei Zhou, Xiaohua Meng, Shujun Ni, Yunxing Yang, Qiong Zhang, Lingjiao Wu, Qiong Chen   +6 more
openaire   +3 more sources

Chromosomal Integration of blaKPC-2 in Proteus mirabilis Clinical Isolates

, 2018
Introduction Over these years, KPC-type beta-lactamases have become one of the most prevalent acquired carbapenemases in Enterobacteriaceae, with the highest incidence in Mediterranean countries, especially Italy and Greece. Historically, blaKPC has been largely reported in high-risk clones of K.
DI PILATO V., CHIARELLI A., BOINETT CJ, RICCOBONO E, HARRIS SR, D'ANDREA MM, THOMSON NR, ROSSOLINI GM, GIANI T   +8 more
openaire   +1 more source

The blaKPC-249-mediated mechanism drives the transition of ST463 Pseudomonas aeruginosa from Ceftazidime-Avibactam sensitivity to resistance during clinical treatment

Frontiers in Cellular and Infection Microbiology
IntroductionCeftazidime-avibactam represents a crucial therapeutic option for managing infections attributable to carbapenem-resistant P. aeruginosa. Nonetheless, the emergence of resistance to ceftazidime-avibactam in P.
Xiaosi Li, Xiaosi Li, Yan Feng, Xiaoyan Wu, Heping Shen, Shumi Shang, Wenting Tang, Fupin Hu, Huijun Liang   +8 more
doaj   +1 more source

Molecular Epidemiology of mcr-1, blaKPC-2, and blaNDM-1 Harboring Clinically Isolated Escherichia coli from Pakistan

Infection and Drug Resistance, 2021
Hazrat Bilal,1 Tayyab Ur Rehman,2 Muhammad Asif Khan,2 Fareeha Hameed,2 Zhang Gao Jian,1 Jianxiong Han,1 Xingyuan Yang1 1Faculty of Health Sciences, Institute of Physical Sciences and Information Technology, Anhui University, Hefei, People’s ...
Bilal H, Rehman TU, Khan MA, Hameed F, Jian ZG, Han J, Yang X   +6 more
doaj  

Prevalence and Distribution Characteristics of blaKPC-2 and blaNDM-1 Genes in Klebsiella pneumoniae

Infection and Drug Resistance, 2020
Xiufeng Zhang,1,2,* Fangping Li,3,* Shiyun Cui,1,2 Lisha Mao,4 Xiaohua Li,3 Furqan Awan,1,2 Weibiao Lv,5 Zhenling Zeng1,2 1College of Veterinary Medicine, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation ...
Zhang X, Li F, Cui S, Mao L, Li X, Awan F, Lv W, Zeng Z   +7 more
doaj