Results 61 to 70 of about 7,824 (162)

Complete genome sequencing and comparative plasmid analysis of KPC-2-producing Klebsiella pneumoniae isolated from hospital sewage water in Japan

Journal of Global Antimicrobial Resistance, 2021
Objectives: The Klebsiella pneumoniae carbapenemase (blaKPC) gene is one of the most widespread carbapenemase genes in the world. However, there are few reports on KPC-producing bacteria in Japan.
Ryotaro Eda, Shotaro Maehana, Aki Hirabayashi, Masaki Nakamura, Takashi Furukawa, Shinsuke Ikeda, Kouji Sakai, Fumiaki Kojima, Kazunari Sei, Masato Suzuki, Hidero Kitasato   +10 more
doaj   +1 more source

Emergence in Japan of an isolate of Klebsiella pneumoniae co-harbouring blaKPC-2 and rmtB

Journal of Global Antimicrobial Resistance, 2019
Here we describe a clinical isolate of Klebsiella pneumoniae ST11 harbouring both blaKPC-2 and rmtB genes in Japan.A carbapenem- and aminoglycoside-resistant K. pneumoniae was isolated from an inpatient in Japan. Whole-genome sequencing (WGS) was performed using an Illumina next-generation sequencer.Minimum inhibitory concentrations (MICs) of meropenem
Hiroki Uchida, Tatsuya Tada, Mari Tohya, Yoshie Sugahara, Akira Kato, Isao Miyairi, Teruo Kirikae   +6 more
openaire   +2 more sources

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu, Shuqing Ma, Fen Xu, Xiangmin Han, Ming Li, Yuanqi Zhu, Sufei Pan, Sujun Hou, Chunqing Ma, Fawen Deng, Shifu Wang, the SPARSS net Working Group, Ningning Ge, Fen Su, Renzhe Li, Fengyan Pei, Chunhua Han, Chengjie Guo, Mingju Hao, Bin Ji, Yan Sun, Xiulei Xue, Mingyan Sun, Yilei Li, Hongyun Cao, Hong He, Fang Wang, Zheng Zhou, Xiaoling Zan, Weiping Zhou, Xuejiao Leng, Chunzhong Dong, Xu Zheng, Shiying Sun, Wei Li, Yongjuan Ma, Jin Li, Xiao‐ying Li, Hongyan Bi, Jinjing Tian, Zhiyong Zhang, Ruifang Yang, Yulong Dai, Xuerong Sun, He Yi, Bo Yu, Fengzhi Bian, Qin Yi, Haiying Chen, Qingling Liu, Guixia Li, Jinfang Guo, Hongning Zhang, Huili Hou, Tao Chen, Zhiwei Liu, Ping Wu, Jiajia Feng, Li‐e Zhang, Junjie Dai, Jie Chen   +60 more
wiley   +1 more source

One Health Surveillance of Antimicrobial Resistance in the Eastern Mediterranean: The Blackchin Guitarfish as a Case Study

GeoHealth, Volume 10, Issue 4, April 2026.
Abstract Antimicrobial resistance (AMR) poses a global One Health challenge, linking human, animal, and environmental health. Marine environments and organisms are increasingly recognized as reservoirs of antimicrobial‐resistant bacteria and mobile genetic elements.
J. Lellouche, H. Di Castro, N. Maschiah, S. Paikin, M. Zvereva, D. Tchernov, A. Scheinin, E. Cohen, D. Meron   +8 more
wiley   +1 more source

Emergence of blaKPC-71 variant and loss of aerobactin-encoding genes (iucABCD-iutA) in ST11-K64 carbapenem-resistant Klebsiella pneumoniae during ceftazidime–avibactam treatment

Journal of Global Antimicrobial Resistance
Objective: To investigate the within-host evolutionary dynamics of resistance and virulence in carbapenem-resistant Klebsiella pneumoniae during ceftazidime-avibactam treatment. Methods: Three K.
Fang-ling Du, Dan-dan Wei, Yong-qing Guo, Peng Liu, Yan-fang Mei, Shan-shan Huang, Qi-sen Huang, Lin-Ping Fan, Yang Liu   +8 more
doaj   +1 more source

Ompk36 disruption and expression of down-regulated blaKPC-2 in Klebsiella pneumoniae clinical isolates carbapenem resistant

Research, Society and Development, 2022
This work investigated the resistance mechanisms that produce different susceptibility profiles in Klebsiella pneumoniae clinical isolates. The genes that encode the main porins in K. pneumoniae, ompK35 and ompK36, and several beta-lactamase genes were analyzed. The expression of these genes was evaluated by quantitative real time PCR (polymerase chain
Paula Mariana Salgueiro de Souza, Ana Caroline Oliveira Alves Ribeiro, Márcia Maria Camargo de Morais, Anna Carolina Soares Almeida   +3 more
openaire   +1 more source

Antibiotic Resistance and Pathogenicity of Vibrio Species in Aquaculture: Implications for Fish Health and Food Safety in LMICs

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Pathogenic Vibrio species isolated from aquaculture environments in low‐ and middle‐income countries exhibit elevated antimicrobial resistance and multiple virulence traits. These findings highlight significant risks to fish health and food safety, underscoring the need for strengthened antimicrobial stewardship, robust biosecurity measures and ...
Asiphe Hobe, Luyanda Msolo, Kingsley Ehi Ebomah, Ishmael Festus Jaja, James Wabwire Oguttu, Anthony Ifeanyi Okoh   +5 more
wiley   +1 more source

Emergence of carbapenem-resistant Pseudomonas aeruginosa ST179 producing both IMP-16 and KPC-2: a case study of introduction from Peru to Spain

Microbiology Spectrum
We describe four cases of a novel carbapenem-resistant Pseudomonas aeruginosa ST179 clone carrying the blaKPC-2 or blaKPC-35 gene together with blaIMP-16, imported from Peru to Spain and isolated from leukemia patients.
Joaquim Viñes, Carlos Lopera, Andrea Vergara, Ignasi Roca, Jordi Vila, Climent Casals-Pascual, José Antonio Martínez, Carolina García-Vidal, Alex Soriano, Cristina Pitart   +9 more
doaj   +1 more source

Validation of Hexaplex Recombinase Polymerase Amplification Assay for the Detection of Carbapenemase Genes in Klebsiella pneumoniae Isolates From Pediatric Inpatients

Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon, Nuntaree Chaichanawongsaroj   +1 more
wiley   +1 more source