Results 71 to 80 of about 7,824 (162)

blaKPC-2 and blaOXA-48 producing Klebsiella pneumoniae found in a Turkish hospital in the Balkans [PDF]

African Journal of Microbiology Research, 2018
Carbapenem-resistant Klebsiella pneumoniae carrying blaKPC-2, blaOxa48, and other metallo-i¢-lactamases (MBLs) are difficult to treat. This study was conducted to study the phenotypic and genotypic features of carbapenem resistance in isolates of K. pneumoniae isolated from a tertiary care hospital in the European region of Turkey.
Bukavaz Sebnem, Budak Metin, Dogan Celik Aygül   +2 more
openaire   +1 more source

The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari, Babak Pourakbari, Mohammad Reza Asadi Karam, Reza Azizian, Mohammad Reza Modaresi, Setareh Mamishi   +5 more
wiley   +1 more source

Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li, Fei Zeng, Jie Zhang, Yuangong Zhang, Wenjuan Yin   +4 more
wiley   +1 more source

Coexistence of blaKPC-2–IncN and mcr-1–IncX4 plasmids in a ST48 Escherichia coli strain in China

Journal of Global Antimicrobial Resistance, 2020
The aim of this study was to explore the genomic content of a blaKPC-2- and mcr-1-harbouring Escherichia coli strain and to clarify the molecular mechanism for the transmission of multidrug resistance.Antimicrobial susceptibility testing was conducted by the broth microdilution method to determine the resistance profile.
Yanfei Wang, Haiyang Liu, Qian Wang, Xiaoxing Du, Yunsong Yu, Yan Jiang   +5 more
openaire   +3 more sources

Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 1, Page 123-134, January 2026.
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita, Laura X. Henao, Sebastián Jaramillo‐Toro, Valentina Quezada, Silvia Restrepo, Juan C. Cruz, Johana Husserl   +6 more
wiley   +1 more source

Molecular Respiratory Pathogen Panels in Lung Transplantation

Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
ABSTRACT Molecular respiratory pathogen panels are an innovative tool for the rapid detection of respiratory pathogens and antimicrobial resistance genes, offering the potential to improve diagnostic accuracy and guide timely antimicrobial therapy.
Andrea Lombardi
wiley   +1 more source

MOESM1 of First report of Klebsiella quasipneumoniae harboring blaKPC-2 in Saudi Arabia

, 2019
Additional file 1: Command-lines for the ...
Hala, Sharif, Chakkiath Antony, Alshehri, Mohammed, Abdulhakeem Althaqafi, Alsaedi, Asim, Areej Mufti, Kaaki, Mai, Baraa Alhaj-Hussein, Hosam Zowawi, Abdulfattah Al-Amri, Arnab Pain   +10 more
openaire   +1 more source

First genome sequence of a blaKPC-2-carrying Citrobacter koseri isolate collected from a patient with diarrhoea

Journal of Global Antimicrobial Resistance, 2018
The blaKPC gene is rarely reported in Citrobacter koseri. Here we report the first draft genome sequence of a blaKPC-2-carrying C. koseri isolate from a patient with diarrhoea.Transferability of the blaKPC-2-bearing plasmid was determined by the filter mating method. The whole genome sequence of C.
Xinjun, Hu, Hao, Xu, Yibing, Shang, Lihua, Guo, Li, Song, Huping, Zhang, Feng, Yue, Hongwei, Jiang, Beiwen, Zheng   +8 more
openaire   +2 more sources

Molecular Characterization and Clonal Analysis of Carbapenem‐Resistant Acinetobacter baumannii: Insights Into Biofilm‐Related Gene Coexistence in Clinical Isolates

BioMed Research International, Volume 2026, Issue 1, 2026.
The emergence of multidrug‐resistant Acinetobacter baumannii (MDR A. baumannii) and biofilm‐producing ability have become a worldwide serious concern. This study is aimed at investigating the clonal relationships, coexistence of carbapenemase‐resistant and biofilm‐related genes, and biofilm biomass capacity in 57 A.
Mahtab Hadadi, Bahram Nasr Esfahani, Arezoo Mirzaei, Sharareh Moghim, Baisakhi Banerjee   +4 more
wiley   +1 more source

Bloodstream Infection Caused by Carbapenemase‐Producing Enterobacterales in a Tertiary Hospital of Colombia: A 6 Year Retrospective Study

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background The global spread of carbapenemase‐producing Enterobacterales (CPE) has emerged as a significant public health challenge. However, epidemiological studies on CPE infections in Latin America remain scarce. This study aims to characterize bloodstream infections (BSIs) caused by CPE at a tertiary hospital over a 6‐year period and analyze the ...
Juan David Cáceres-González, Jorge Álvarez, Lorena Matta-Cortés, Ernesto Martínez-Buitrago, Johann A. Ospina-Galindez, Claudia C. Paredes-Amaya, Bishnu P. Marasini   +6 more
wiley   +1 more source