Results 51 to 60 of about 856,452 (279)

Angular size and emission time scales of relativistic fireballs [PDF]

, 1997
The detection of delayed X-ray, optical and radio emission, ``afterglow,'' associated with gamma-ray bursts (GRBs) is consistent with models, where the bursts are produced by relativistic expanding blast waves, driven by expanding fireballs at ...
Eli Waxman, Wijers A. M. J.
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Occupational Blast Wave Exposure During Multiday 0.50 Caliber Rifle Course

Frontiers in Neurology, 2019
Research on blast overpressure (BOP) experienced by military personnel in operations like breaching, identifies transient, measurable effects on operator readiness.
Maciej Skotak, Christina LaValle, Christina LaValle, Anthony Misistia, Anthony Misistia, Michael J. Egnoto, Namas Chandra, Gary Kamimori   +7 more
doaj   +1 more source

Gamma-ray burst afterglow blast waves

, 2018
The various stages of baryonic gamma-ray burst afterglow blast waves are reviewed. These are responsible for the afterglow emission from which much of our understanding of gamma-ray bursts derives.
van Eerten, Hendrik
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Numerical Study of Pressure Attenuation Effect on Tunnel Structures Subjected to Blast Loads

Applied Sciences, 2021
This study used experimental and numerical simulation methods to discuss the attenuation mechanism of a blast inside a tunnel for different forms of a tunnel pressure reduction module under the condition of a tunnel near-field explosion.
Cheng-Wei Hung, Ying-Kuan Tsai, Tai-An Chen, Hsin-Hung Lai, Pin-Wen Wu   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Dysregulation of Retinal Melatonin Biosynthetic Pathway and Differential Expression of Retina-Specific Genes Following Blast-Induced Ocular Injury in Ferrets

Neurology International
Background/Objectives: Blast-induced traumatic ocular injuries (bTOI) pose a significant risk to military and civilian populations, often leading to visual impairment or blindness.
Chetan Pundkar, Rex Jeya Rajkumar Samdavid Thanapaul, Manoj Govindarajulu, Gaurav Phuyal, Joseph B. Long, Peethambaran Arun   +5 more
doaj   +1 more source

Blast-Related Traumatic Brain Injury: Current Concepts and Research Considerations

Journal of Experimental Neuroscience, 2019
Traumatic brain injury (TBI) is a well-known consequence of participation in activities such as military combat or collision sports. But the wide variability in eliciting circumstances and injury severities makes the study of TBI as a uniform disease ...
Daniel W Bryden, Jessica I Tilghman, Sidney R Hinds   +2 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source