Results 51 to 60 of about 461,778 (244)
Non-linear Dynamic Analysis of Steel Hollow I-core Sandwich Panel under Air Blast Loading [PDF]
Civil Engineering Infrastructures Journal, 2015 In this paper, the non-linear dynamic response of novel steel sandwich panel with hollow I-core subjected to blast loading was studied. Special emphasis is placed on the evaluation of midpoint displacements and energy dissipation of the models.
Asghar Vatani Oskouei, Foad Kiakojouri
doaj +1 more source
The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]
, 2002 Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette +2 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Blast Overpressure-Induced Neuroinflammation and Axonal Injury in the Spinal Cord of Ferrets
Brain SciencesBackground: Blast-induced spinal cord injuries (bSCI) account for 75% of all combat-related spinal trauma and are associated with long-term functional impairments.
Gaurav Phuyal +7 more
doaj +1 more source
Frontiers in Neurology, 2021 Blast traumatic brain injury is ubiquitous in modern military conflict with significant morbidity and mortality. Yet the mechanism by which blast overpressure waves cause specific intracranial injury in humans remains unclear.
Scott T. Miller +6 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Frontiers in Neurology, 2021 Although blast exposure has been recognized as a significant source of morbidity and mortality in military populations, our understanding of the effects of blast exposure, particularly low-level blast (LLB) exposure, on health outcomes remains limited ...
Jennifer N. Belding +13 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Identification of rice blast disease-suppressing bacterial strains from the rhizosphere of rice grown in Pakistan. [PDF]
, 2009 Sixteen bacterial strains isolated from the roots and rhizosphere of rice plants growing in saline and non-saline soils from the Shorkot area of Pakistan were tested for their ability to promote plant growth and reduce the incidence of rice blast disease.
Price, Adam H. +3 more
core +4 more sources
Sex as a Biological Variable in Preclinical Modeling of Blast-Related Traumatic Brain Injury
Frontiers in Neurology, 2020 Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority.
Joseph T. McCabe +3 more
doaj +1 more source