Results 11 to 20 of about 1,572 (142)

Acute Myeloid Leukemia With Plasmacytoid Differentiating Cutaneous Lesions: A Case of Double Identity or Active Transformation

eJHaem
Introduction Acute myeloid leukemia (AML) with plasmacytoid dendritic cell differentiation (pDC‐AML) is a newly described subtype of leukemia with features resembling blastic plasmacytoid dendritic cell neoplasm (BPDCN).
Benjamin J. Lee, Shawn P. Griffin, Deepa Jeyakumar, Ashley Gamayo, Sherif A. Rezk, Kiran Naqvi   +5 more
doaj   +2 more sources

Hematopoietic effects of tagraxofusp in treatment-naive patients with blastic plasmacytoid dendritic cell neoplasm. [PDF]

Cancer
Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic neoplasm that expresses CD123, is often observed in the bone marrow (BM), as well as skin, blood, and viscera. Tagraxofusp, a first‐in‐class CD123‐targeted therapy, is the only drug approved to treat BPDCN.
Konopleva M, Pemmaraju N, Sweet KL, Stein AS, Rizzieri DA, Wang ES, Vasu S, Rosenblat T, Zuurman M, Gupta I, Lane AA.   +10 more
europepmc   +2 more sources

Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations

Radiology Case Reports, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive myeloid malignancy thought to be derived from precursor plasmacytoid dendritic cells. Rapid progression and poor prognosis have been known.
Kyohei Yoshioka, Ryo Kurokawa, Shiori Amemiya, Hiroaki Koyamaa, Kensuke Matsuda, Akira Honda, Mineo Kurokawa, Aya Shinozaki-Ushiku, Osamu Abe   +8 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm [PDF]

Blood, 2012
![Figure][1] An 81-year-old man had multiple skin lesions (brown-red plaques on the face, abdomen, and back) and asthenia. There was no hepatosplenomegaly or adenopathy. Despite normal blood count values, the peripheral smear contained blasts (7%).
Fanny, Angelot-Delettre, Francine, Garnache-Ottou   +1 more
  +6 more sources

A misdiagnosed case of blastic plasmacytoid dendritic cell neoplasm experiencing multiple recurrences who underwent allogeneic stem cell transplantation: a case report

Journal of Medical Case Reports, 2021
Background Blastic plasmacytoid dendritic cell neoplasm represents a rare type of hematologic malignancy that often manifests itself through various skin lesions. It commonly affects the elderly male population.
Fateme Salemi, Seyed Mohammad Reza Mortazavizadeh, Seyyedmohammadsadeq Mirmoeeni, Amirhossein Azari Jafari, Farid Kosari, Seyed Sina Naghibi Irvani   +5 more
doaj   +1 more source

Pathomorphological and clinical characteristics of blastic plasmocytoid dendritic cell neoplasm. Case report

Терапевтический архив, 2022
The paper reveals the 5 cases date about blastic plasmacytoid dendritic cell neoplasm. The presented information demonstrates morphological, immunohistochemical data and clinical manifestations.
Andrei A. Sherstnev, Alla M. Kovrigina, Tatiana I. Solovyova, Tatiana N. Moiseeva   +3 more
doaj   +1 more source

A case of blastic plasmacytoid dendritic cell neoplasm in a young male with atypical cutaneous findings [PDF]

JAAD Case Reports
Olamide Sonuga, BS, Aneri B. Patel, BS, Briana Halle Brady, MD, Linda Doan, MD, PhD, Janellen Smith, MD   +4 more
doaj   +2 more sources

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy derived from the precursors of plasmacytoid dendritic cells.
Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva   +32 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm BPDCN

Hematology, Transfusion and Cell Therapy, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. BPDCN is most often characterized by its presentation with cutaneous lesions which are often asymptomatic, can be
Hanan Hamed
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms

eJHaem, 2022
This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a
Siba El Hussein, Mariko Yabe, Wei Wang, Naveen Pemmaraju, Sanam Loghavi, Fatima Zahra Jelloul, Hong Fang, L. Jeffrey Medeiros, W. Richard Burack, Andrew G. Evans, Jane L. Liesveld, John M. Bennett   +11 more
doaj   +1 more source