Results 121 to 130 of about 122,819 (363)

A single-cell RNA expression map of coronavirus receptors and associated factors in developing human embryos [PDF]

arXiv, 2020
To predict if developing human embryos are permissive to coronaviruses, we analyzed publicly available single cell RNA-seq datasets of zygotes, 4-cell, 8-cell, morula, inner cell mass, epiblast, primitive endoderm and trophectoderm for the coronavirus receptors (ACE2, BSG, DPP4 and ANPEP), the Spike protein cleavage enzymes (TMPRSS2, CTSL).
arxiv  

Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]

, 2009
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R, Bradley, Allan, Liang, Qi, Lloyd, Kent C, Moran, Jennifer L, Pettitt, Stephen J, Prosser, Haydn M, Rairdan, Xin Y, Skarnes, William C   +8 more
core   +1 more source

Development of node architecture and emergence of molecular organizer characteristics in the pig embryo

Developmental Dynamics, EarlyView.
Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush, Christoph Viebahn, Nikoloz Tsikolia   +2 more
wiley   +1 more source

Genetic modification of the ant Lasius niger using CRISPR‐Cas9 technology

Insect Molecular Biology, Volume 32, Issue 1, Page 11-25, February 2023., 2023
We successfully modified the cinnabar gene in the black garden ant (Lasius niger) resulting in an abnormal eye colour in mutated adults. We provide a detailed protocol to collect ant eggs, inject them with CRISPR‐Cas9 construct, rear the eggs to adults and verify mutants by sequencing the target gene.
Mauno Konu, Jonna Kulmuni, Lumi Viljakainen   +2 more
wiley   +1 more source

From implantation to birth: insight into molecular melatonin functions [PDF]

, 2018
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland, acting as a neuroendocrine transducer of photoperiodic information during the night.
Carlomagno, Gianfranco, Minini, Mirko, Tilotta, Marco, Unfer, Vittorio   +3 more
core   +1 more source

Association between blastocyst morphology and outcome of single-blastocyst transfer [PDF]

Reproductive BioMedicine Online, 2013
The aim of this study was to assess the ability of three individual blastocyst morphology parameters - expansion and hatching (EH) stage, inner cell mass (ICM) grade and trophectoderm grade - to predict outcome of a cycle with single-blastocyst transfer. The study was a secondary analysis of data prospectively collected in a large multicentre trial.
Bjarke Mirner Klein, Søren Ziebe, Kersti Lundin, Joan-Carles Arce, L. Helmgaard, Maria José Gómez Cuesta, Etienne Van den Abbeel, Basak Balaban   +7 more
openaire   +2 more sources

Uterine glands impact uterine receptivity, luminal fluid homeostasis and blastocyst implantation

Scientific Reports, 2016
Uterine glands are essential for pregnancy in mice and likely humans, because they secrete or transport bioactive substances that regulate uterine receptivity for blastocyst implantation.
A. M. Kelleher, G. Burns, S. Behura, Guoyao Wu, T. Spencer   +4 more
semanticscholar   +1 more source

A network of transient domains for breaking symmetry during anterior–posterior axis formation in the porcine embryo

Developmental Dynamics, EarlyView.
Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger, Nikoloz Tsikolia, Christoph Viebahn   +2 more
wiley   +1 more source

Genetically engineered multicistronic allele of Pmel yielding highly specific CreERT2‐mediated recombination in the melanocyte lineage

Pigment Cell &Melanoma Research, Volume 36, Issue 1, Page 71-77, January 2023., 2023
Abstract Genetic approaches that allow lineage tracing are essential to our future understanding of melanocytes and melanoma. To date, the approaches used to label melanocytes in mice have relied on random integration of transgenes driven by the promoters of the Tyrosinase and Dopachrome tautomerase genes, knock‐in to the Dopachrome tautomerase locus ...
Emma L. Wilkinson, Louise C. Brennan, Olivia J. Harrison, Zoe Crane‐Smith, Philippe Gautier, Margaret A. Keighren, Peter Budd, Karthic Swaminathan, Laura M. Machesky, Sarah L. Allinson, Ian J. Jackson, Richard L. Mort   +11 more
wiley   +1 more source

Pregnancy and birth outcomes following fresh or vitrified embryo transfer according to blastocyst morphology and expansion stage, and culturing strategy for delayed development.

Human Reproduction, 2016
STUDY QUESTION How do live birth rates (LBRs), following fresh and vitrified/warmed embryo transfer, compare according to morphological grade, developmental stage and culturing strategy of human blastocysts in vitro? SUMMARY ANSWER Equivalent LBRs were
B. Wirleitner, M. Schuff, A. Stecher, M. Murtinger, P. Vanderzwalmen   +4 more
semanticscholar   +1 more source