Results 41 to 50 of about 110,172 (282)

In vitro production of bovine embryos derived from individual donors in the Corral® dish [PDF]

, 2017
Background: Since the identity of the embryo is of outmost importance during commercial in vitro embryo production, bovine oocytes and embryos have to be cultured strictly per donor.
A Cebrian-Serrano, Ann Van Soom, C Carolan, C O’Neill, C O’Neill, E Wydooghe, Eline Wydooghe, EM O’Doherty, Erik Mullaart, G Vajta, Hiemke M. Knijn, I Donnay, IGF Goovaerts, J Merton, JF Hasler, JF Hasler, JHF Pontes, JS Merton, K Matsuura, L Ferry, LJ Ding, M Hoelker, M Lane, Maaike Catteeuw, ML Reed, N Gopichandran, NK Khurana, P George, PEJ Bols, PEJ Bols, R Boni, R Roover De, RB Gilchrist, S Spanos, SA Machado, SJ Dai, T Ebner, T Fujita, WG Feng   +38 more
core   +2 more sources

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

Synchrony of the first division as an index of the blastocyst formation rate during embryonic development

Reproductive Medicine and Biology, 2018
Purpose To devise an uninvasive selection system for human embryos with high developmental potential after a single oocyte retrieval cycle by comparing the in vitro and in vivo effectiveness of first division synchrony against subsequent embryonic ...
Yamato Mizobe, Makoto Tokunaga, Naoto Oya, Reiko Iwakiri, Naomi Yoshida, Yumi Sato, Nanase Onoue, Yuji Ezono   +7 more
doaj   +1 more source

Neurotrophin-4 promotes the specification of trophectoderm lineage after parthenogenetic activation and enhances porcine early embryonic development

Frontiers in Cell and Developmental Biology, 2023
Neurotrophin-4 (NT-4), a neurotrophic factor, appears to affect early embryonic development because it is secreted not only by neurons but also by oviductal and uterine epithelial cells. However, no studies have characterized the effects of NT-4 on early
Mirae Kim, Mirae Kim, Joohyeong Lee, Joohyeong Lee, Lian Cai, Lian Cai, Lian Cai, Hyerin Choi, Hyerin Choi, Dongjin Oh, Dongjin Oh, Ali Jawad, Ali Jawad, Sang-Hwan Hyun, Sang-Hwan Hyun, Sang-Hwan Hyun   +15 more
doaj   +1 more source

Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. [PDF]

, 2006
Cellular ATP is mainly generated through mitochondrial oxidative phosphorylation, which is dependent on mitochondrial DNA (mtDNA). We have previously demonstrated the importance of oocyte mtDNA for porcine and human fertilization.
Alexander, Jan, Altieri, Andrea, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dall'Asta, Chiara, Dinovi, Michael, Edler, Lutz, EFSA Panel on Contaminants in the Food Chain (CONTAM), Eriksen, Gunnar Sundstøl, Grasl-Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Knutsen, Helle Katrine, Nebbia, Carlo Stefano, Oswald, Isabelle P., Petersen, Annette, Roldán-Torres, Ruth, Rose, Martin, Roudot, Alain-Claude, Schwerdtle, Tanja, Taranu, Ionelia, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather   +26 more
core   +6 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle

The Journal of Reproduction and Development
The induction of the germ cell lineage from pluripotent stem cells (in vitro gametogenesis) will help understand the mechanisms underlying germ cell differentiation and provide an alternative source of gametes for reproduction.
Atsushi SHIRASAWA, Masafumi HAYASHI, Mayumi SHONO, Atsushi IDETA, Takashi YOSHINO, Katsuhiko HAYASHI   +5 more
doaj   +1 more source

Leukemia Inhibitory Factor Stimulates Primitive Endoderm Expansion in the Bovine Inner Cell Mass

Frontiers in Animal Science, 2021
Previous work determined that bovine interleukin-6 (IL6) increases inner cell mass (ICM), primitive endoderm (PE), and total cell number in in vitro produced (IVP) bovine blastocysts.
Lydia K. Wooldridge, Alan D. Ealy
doaj   +1 more source

NaNog: A pluripotency homeobox (master) molecule. [PDF]

, 2015
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE, Allouba, MH, ElGuindy, AM, Krishnamoorthy, N, Yacoub, MH   +4 more
core   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source