Results 41 to 50 of about 109,750 (256)
In vitro production of bovine embryos derived from individual donors in the Corral® dish [PDF]
Background: Since the identity of the embryo is of outmost importance during commercial in vitro embryo production, bovine oocytes and embryos have to be cultured strictly per donor.
A Cebrian-Serrano +38 more
core +2 more sources
Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica +3 more
wiley +1 more source
Purpose To devise an uninvasive selection system for human embryos with high developmental potential after a single oocyte retrieval cycle by comparing the in vitro and in vivo effectiveness of first division synchrony against subsequent embryonic ...
Yamato Mizobe +7 more
doaj +1 more source
Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. [PDF]
Cellular ATP is mainly generated through mitochondrial oxidative phosphorylation, which is dependent on mitochondrial DNA (mtDNA). We have previously demonstrated the importance of oocyte mtDNA for porcine and human fertilization.
Alexander, Jan +26 more
core +5 more sources
Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony +3 more
core +1 more source
Neurotrophin-4 (NT-4), a neurotrophic factor, appears to affect early embryonic development because it is secreted not only by neurons but also by oviductal and uterine epithelial cells. However, no studies have characterized the effects of NT-4 on early
Mirae Kim +15 more
doaj +1 more source
Genetic Normalization of Differentiating Aneuploid Human Embryos [PDF]
Early embryogenesis involves a series of dynamic processes, many of which are currently not well described or understood. Aneuploidy and aneuploid mosaicism, a mixture of aneuploid and euploid cells within one embryo, in early embryonic development are ...
Andrew Barker +8 more
core +1 more source
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang +12 more
wiley +1 more source
Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle
The induction of the germ cell lineage from pluripotent stem cells (in vitro gametogenesis) will help understand the mechanisms underlying germ cell differentiation and provide an alternative source of gametes for reproduction.
Atsushi SHIRASAWA +5 more
doaj +1 more source
Leukemia Inhibitory Factor Stimulates Primitive Endoderm Expansion in the Bovine Inner Cell Mass
Previous work determined that bovine interleukin-6 (IL6) increases inner cell mass (ICM), primitive endoderm (PE), and total cell number in in vitro produced (IVP) bovine blastocysts.
Lydia K. Wooldridge, Alan D. Ealy
doaj +1 more source

