Results 41 to 50 of about 93,689 (293)

Aneuploidy in the Human Blastocyst

Cytogenetic and Genome Research, 2011
Studies of human cleavage stage embryos, 3 days after fertilization of the oocyte, have revealed remarkably high levels of chromosome abnormality. In addition to meiotic errors derived from the gametes, principally the oocyte, mitotic errors occurring after fertilization are also common, leading to widespread chromosomal mosaicism.
Fragouli, E, Wells, D
openaire   +3 more sources

Which Blastocyst to Be Biopsied? - Blastocyst Stage and Quality

Fertility & Reproduction, 2023
This talk is an engaging format to address crucial aspects of selecting the most suitable blastocyst for biopsy to optimize the success of PGT procedures and successful pregnancies. The talk commences with an overview of various blastocyst stages and relevant morphological characteristics, elucidating the critical developmental milestones and key ...
openaire   +2 more sources

Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies

Frontiers in Cell and Developmental Biology, 2019
To become fertile, mammalian sperm must undergo a series of biochemical and physiological changes known as capacitation. These changes involve crosstalk between metabolic and signaling pathways and can be recapitulated in vitro.
Felipe A. Navarrete, Luis Aguila, David Martin-Hidalgo, David Martin-Hidalgo, Darya A. Tourzani, Guillermina M. Luque, Goli Ardestani, Francisco A. Garcia-Vazquez, Francisco A. Garcia-Vazquez, Lonny R. Levin, Jochen Buck, Alberto Darszon, Mariano G. Buffone, Jesse Mager, Rafael A. Fissore, Ana M. Salicioni, María G. Gervasi, Pablo E. Visconti   +17 more
doaj   +1 more source

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities [PDF]

, 2014
STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight or obese women are smaller than those from women of healthy weight, yet post-fertilization ...
Leary, C., Leary, Christine, Leese, H. J., Leese, Henry J., Sturmey, R. G., Sturmey, Roger G.   +5 more
core   +1 more source

Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts [PDF]

, 2017
During the transit through the oviduct, the early embryo initiates an extensive DNA methylation reprogramming of its genome. Given that these epigenetic modifications are susceptible to environmental factors, components present in the oviductal milieu ...
Barrera, Antonio Daniel, Fonseca Balvís, Noelia, Garcia, Elina Vanesa, Gutiérrez Adan, Alfonso, Hamdi, Meriem, López Cardona, Ángela Patricia, Rizos, Dimitrios, Sánchez Calabuig, María Jesús   +7 more
core   +1 more source

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

eLife, 2018
Early mouse development is regulated and accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2).
Jan J Zylicz, Maud Borensztein, Frederick CK Wong, Yun Huang, Caroline Lee, Sabine Dietmann, M Azim Surani   +6 more
doaj   +1 more source

The Effect of Prolonged Culture of Chromosomally Abnormal Human Embryos on The Rate of Diploid Cells [PDF]

International Journal of Fertility and Sterility, 2016
Background A decrease in aneuploidy rate following a prolonged co-culture of human blastocysts has been reported. As co-culture is not routinely used in assisted reproductive technology, the present study aimed to evaluate the effect of the prolonged ...
Masood Bazrgar, Hamid Gourabi, Poopak Eftekhari-Yazdi, Hamed Vazirinasab, Mostafa Fakhri, Fatemeh Hassani, Mohamad Chehrazi, Mojtaba Rezazadeh Valojerdi   +7 more
doaj   +1 more source

Regulation of blastocyst formation

Frontiers in Bioscience, 2001
Preimplantation or pre-attachment development encompasses the "free"-living period of mammalian embryogenesis, which directs development of the zygote through to the blastocyst stage. Blastocyst formation is essential for implantation, establishment of pregnancy and is a principal determinant of embryo quality prior to embryo transfer.
Watson, A J, Barcroft, L C
openaire   +5 more sources

Effect of equilibration time on clinical and neonatal outcomes in human blastocysts vitrification

Reproductive Medicine and Biology, 2020
Purpose Prolonged exposure to equilibration solutions may be detrimental to an embryo's developmental potential, whereas a shorter exposure may affect the penetration of cryoprotectants into blastomeres.
Shingo Mitsuhata, Momoko Hayashi, Yoshitaka Fujii, Hiroaki Motoyama, Yuji Endo   +4 more
doaj   +1 more source

Survival of bovine blastocysts produced in vitro and vitrified in vitri-tip and vitri-top devices. [PDF]

SPERMOVA, 2019
Vitrification is a new technique that has many potential advantages in mammalian oocytes and embryos. In the present work, the objective was to compare of post thawing survival rate by of blastocysts vitrified in vitro in two devices.
R. Condori , C. Quispe, E. Ancco , D. Dipaz, E. Mellisho   +4 more
doaj   +1 more source