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Znaczenie białka macierzy jądrowej BLCA-4 w raku pęcherza moczowego

Postępy Higieny i Medycyny Doświadczalnej, 2017
openaire   +1 more source

Pathogenic and Diagnostic Potential of BLCA-1 and BLCA-4 Nuclear Proteins in Urothelial Cell Carcinoma of Human Bladder [PDF]

Advances in Urology, 2012
Transitional cell carcinoma (TCC) of the bladder is one of the most common malignancies of genitourinary tract. Patients with bladder cancer need a life-long surveillance, directly due to the relatively high recurrence rate of this tumor. The use of cystoscopy represents the gold standard for the followup of previously treated patients.
Matteo Santoni, Daniele Minardi, Massimo Nabissi   +2 more
exaly   +9 more sources

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Chromium (VI) promotes EMT by regulating FLNA in BLCA

Environmental Toxicology, 2021
AbstractHexavalent chromium (Cr (VI)), which is a recognized human carcinogen, is widely used in industrial production of raw materials. Evidence verifies that environmental contaminants in the urine can induce malignant transformation in the urinary bladder tract, and our data indicate that Cr (VI) could promote the proliferation and migration and ...
Fei Sheng
exaly   +3 more sources

The comprehensive and systematic identification of BLCA-specific SF-regulated, survival-related AS events

Gene, 2022
Bladder urothelial carcinoma (BLCA) is a complex disease with high morbidity and mortality. Changes in alternative splicing (AS) and splicing factor (SF) can affect gene expression, thus playing an essential role in tumorigenesis. This study downloaded 412 patients' clinical information and 433 samples of transcriptome profiling data from TCGA.
Ka Chun Wong, Zhe Liu
exaly   +3 more sources

CLINICAL USEFULNESS OF THE NOVEL MARKER BLCA-4 FOR THE DETECTION OF BLADDER CANCER

Journal of Urology, 2000
Previous studies at our laboratory identified 6 bladder cancer specific nuclear matrix proteins termed BLCA-1 to 6. We recently developed an immunoassay that detects the bladder cancer specific nuclear matrix protein BLCA-4. We analyzed urine samples from patients with bladder cancer, those with spinal cord injury and normal volunteers to determine the
Sheldon Bastacky, Robert H Getzenberg, Badrinath R Konety   +2 more
exaly   +3 more sources

USE OF THE NOVEL MARKER BLCA-1 FOR THE DETECTION OF BLADDER CANCER

Journal of Urology, 2005
Bladder cancer specific nuclear structural alterations have been identified. We examined the expression pattern of one of these proteins, BLCA-1, in tissue and urine samples from individuals with bladder cancer as well as in samples from normal controls.BLCA-1 sequence data were used to produce antibodies to this protein, which were used in immunoblot ...
Robert H Getzenberg
exaly   +3 more sources

Deciphering the role of PTPN6 in aberrant signaling and BLCA prognosis

Discover Biotechnology
Sajjad Hussain
exaly   +2 more sources