DEVELOPMENT AND APPLICATION OF AN IN VITRO PHARMACODYNAMIC MODEL FOR USE IN EXAMINING NOVEL DOSING STRATEGIES FOR AMOXICILLIN VS. BETA-LACTAMASE NEGATIVE AMPICILL1N RESISTANT HAEMOPIHLUS INFLUENZAE [PDF]
, 2006 An in vitro pharmacodynamic model was designed to investigate the pharmacokinetic/pharmacodynamic (PK/PD) relationships of pulsatile, continuous infusion and traditional divided dose regimens of amoxicillin versus two strains of beta- lactamase-negative ...
Maland, Matthew C.
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Levofloxacin vs. Azithromycin Pharmacodynamic Activity Against S. pneumoniae and H. influenzae with Decreased Susceptibility to Amoxicillin/Clavulanic Acid [PDF]
, 2007 Resistant clones/phenotypes are putting into question the activity of commonly used beta-lactams, thus prompting the need for alternative options. A 500 mg levofloxacin vs.
Alou Cervera, Luis +9 more
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An evaluation of SNP-based PCR methods for the detection of β-lactamase-negative ampicillin-resistant Haemophilus influenzae. [PDF]
, 2012 Forty-four previously characterized strains of Haemophilus influenzae were used to evaluate the specificity of previously published SNP PCR primers for the detection of the N526K substitution in PBP3 of BLNAR isolates using real-time PCR. Hasegawa et al.
Kunde, Dale +2 more
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High prevalence of nasal carriage of β-lactamase-negative ampicillin-resistant Haemophilus influenzae in healthy children in Korea [PDF]
, 2012 This study investigated the carriage of antimicrobial resistant Haemophilus influenzae in 582 healthy children attending kindergarten or elementary school at four intervals over a 9-month period in Seoul, Korea.
YU, J. Y. +5 more
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Characterisation of Resistance to ß-Lactam Antibiotics in a Population of Haemophilus Influenzae [PDF]
Increased global β-lactam resistance in H. influenzae is due to the production of plasmid mediated TEM and ROB β-lactamases and/or reduced affinity penicillin binding proteins (PBPs). β-lactamase-negative, ampicillin resistant (BLNAR) isolates have amino
Walker, R.M.
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PCR screening for the N526K substitution in isolates of Haemophilus influenzae and Haemophilus haemolyticus [PDF]
, 2013 Objectives: Firstly, to evaluate the current PBP3-S primers of Hasegawa et al. (Microb Drug Resist 2003; 9: 39–46) and develop new primers for the amplification of N526 in isolates of Haemophilus haemolyticus. Secondly, to develop a new PCR assay for the
Witherden, EA (15540092) +2 more
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Characterization of extended-spectrum beta-lactamase-producing isolates of Haemophilus parainfluenzae [PDF]
, 2008 Objectives: To characterize the â-lactam resistance mechanisms of two clinical isolates of cefotaxime-resistant Haemophilus parainfluenzae recovered from patients in South Africa.
Pitout, MJ (15518579) +5 more
core
Clinical features and subdural lesions in childhood onset Haemophilus influenzae meningitis [PDF]
, 2010 It becomes difficult to treat the onset of childhood Haemophilus influenza type b( Hib) meningitis due tothe appearance of b-lactamase negative ampicilin resistance( BLNAR).
Imataka, George +6 more
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Haemophilus influenzae blood-stream infection and third-generation cephalosporin susceptibility testing: a comparative case study using EUCAST and CLSI guidelines. [PDF]
Access Microbiol, 2023 Merlino J +7 more
europepmc +1 more source