Results 51 to 60 of about 67,281 (289)

A New Quantum-Based Building Block for Designing a Nano-Circuit with Lower Complexity [PDF]

open access: yesInformacije MIDEM, 2023
Y. Li   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Complex wireframe DNA nanostructures from simple building blocks [PDF]

open access: yesNature Communications, 2019
AbstractDNA nanostructures with increasing complexity have showcased the power of programmable self-assembly from DNA strands. At the nascent stage of the field, a variety of small branched objects consisting of a few DNA strands were created. Since then, a quantum leap of complexity has been achieved by a scaffolded ‘origami’ approach and a scaffold ...
Wen Wang   +9 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Deep Residual Squeeze and Excitation Network for Remote Sensing Image Super-Resolution

open access: yesRemote Sensing, 2019
Recently, deep convolutional neural networks (DCNN) have obtained promising results in single image super-resolution (SISR) of remote sensing images. Due to the high complexity of remote sensing image distribution, most of the existing methods are not ...
Jun Gu   +4 more
doaj   +1 more source

Life’s building blocks: the modular path to multiscale complexity

open access: yesFrontiers in Systems Biology
Modularity, the structuring of systems into discrete, interconnected units, is a fundamental organizing principle in biology across multiple scales. Recent progress in understanding the role of modularity as an evolutionary mechanism and a key driver of biological complexity has highlighted its importance in shaping the structure and function of living
Saúl Huitzil   +4 more
openaire   +4 more sources

Building Blocks of the Nexin-Dynein Regulatory Complex in Chlamydomonas Flagella [PDF]

open access: yesJournal of Biological Chemistry, 2011
The directional flow generated by motile cilia and flagella is critical for many processes, including human development and organ function. Normal beating requires the control and coordination of thousands of dynein motors, and the nexin-dynein regulatory complex (N-DRC) has been identified as an important regulatory node for orchestrating dynein ...
Jianfeng, Lin   +6 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Design agents and the need for high-dimensional perception

open access: yes, 2011
Designed artefacts may be quantified by any number of measures. This paper aims to show that in doing so, the particular measures used may matter very little, but as many as possible should be taken.
Hanna, S, Sean Hanna
core   +1 more source

How small are building blocks of complex networks

open access: yesCoRR, 2009
Network motifs are small building blocks of complex networks. Statistically significant motifs often perform network-specific functions. However, the precise nature of the connection between motifs and the global structure and function of networks remains elusive.
Almerima Jamakovic   +4 more
openaire   +2 more sources

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