Results 61 to 70 of about 67,281 (289)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Survey on compressed sensing over the past two decades
Memories - Materials, Devices, Circuits and Systems, 2023 Compressed Sensing (CS) is a novel data acquisition theorem exploiting the signals sparsity differing from traditional Nyquist theorem in the ability of obtaining all information of such signal in fewer samples.
Sherif Hosny +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
In situ surface functionalisation of scaffolds using block copolymer self-assembly [PDF]
, 2013 Understanding human mesenchymal stem cell (hMSC) adhesion and differentiation in three-dimensional matrices in vitro is important for potential regenerative medicine and stem cell therapies.
Viswanathan, Priyalakshmi
core
Integral attack on HIGHT block cipher
Tongxin xuebao, 2016 The security of HIGHT block cipher under integral attack was studied. Firstly, the flaw in the existing results on building the distinguisher was corrected. And a new 11-round integral distinguisher of HIGHT was built.
Jian-sheng GUO +3 more
doaj +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Simulation of urban microclimate with uhiSolver: software validation using simplified material data
Ecological Processes, 2021 Background Increasing urbanization as well as global warming requires an investigation of the influence of different construction methods and ground surfaces on the urban heat island effect (UHI effect). The extent of the influence of the urban structure,
Florian Teichmann +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Establishing an Appropriate Level of Detail (LoD) for a Building Information Model (BIM) – West Block, Parliament Hill, Ottawa, Canada [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2014 In 2011, Public Works and Government Services Canada (PWGSC) embarked on a comprehensive rehabilitation of the historically significant West Block of Canada’s Parliament Hill.
S. Fai, J. Rafeiro
doaj +1 more source