Results 71 to 80 of about 67,281 (289)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Isomorphism versus commensurability for a class of finitely presented groups

open access: yes, 2014
We construct a class of finitely presented groups where the isomorphism problem is solvable but the commensurability problem is unsolvable. Conversely, we construct a class of finitely presented groups within which the commensurability problem is ...
Arzhantseva, Goulnara   +2 more
core   +1 more source

MDA-RSM: multi-directional adaptive remote sensing mamba for building extraction

open access: yesGIScience & Remote Sensing
Buildings are core carriers of urbanization and socio-economic development. Accurate extraction of buildings from remote sensing imagery is crucial for urban planning, population statistics, and economic assessment. However, existing convolutional neural
Ming Zhao   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Understanding the building blocks of avian complex cognition

open access: yes, 2021
In contrast to what one might expect from such a small brain, the birdbrain is capable of complex cognition. This thesis studied the building blocks of avian cognition by investigating the comparative anatomy of the avian analogue to the prefrontal cortex, the nidopallium caudolaterale (NCL) and by estimating the neuronal energy budget.
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Building block based spatial topology synthesis method for large stroke flexure hinges [PDF]

open access: yes, 2017
Large stroke flexure mechanisms inherently lose stiffness in supporting directions when deflected. A systematic approach to synthesize such hinges is currently lacking.
Brouwer, Dannis Michel   +6 more
core   +1 more source

Robo-Matter towards reconfigurable multifunctional smart materials

open access: yesNature Communications
Maximizing materials utilization efficiency via enhancing their reconfigurability and multifunctionality offers a promising avenue in addressing the global challenges in sustainability.
Jing Wang   +15 more
doaj   +1 more source

Home - About - Disclaimer - Privacy