Results 81 to 90 of about 857,044 (346)
The current student (and civil) protest in Serbia started at the end of November 2024, as a reaction to the fall of the canopy of the Railway station in Novi Sad, during which sixteen people lost their lives.
Jovana Čikić, Ana Bilinović Rajačić
doaj +1 more source
Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury (EBB-TBI): Protocol for a Phase 2a Intervention Design Study [PDF]
Matt Thomas +6 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Les agents français dans la Plata
This article aims to highlight the political and diplomatic impact of the stigma of barbarism affecting Juan Manuel Rosas, Governor of Buenos Aires, during the Plata’s blockade between 1838 and 1840. This rosist barbarism, first disseminated in France by
Clara María Avendaño Marín
doaj +1 more source
Bipolar spin blockade and coherent state superpositions in a triple quantum dot
Spin qubits based on interacting spins in double quantum dots have been successfully demonstrated. Readout of the qubit state involves a conversion of spin to charge information, universally achieved by taking advantage of a spin blockade phenomenon ...
Busl, M. +10 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The Addition Spectrum of a Lateral Dot from Coulomb and Spin Blockade Spectroscopy
Transport measurements are presented on a class of electrostatically defined lateral dots within a high mobility two dimensional electron gas (2DEG).
Ciorga, M. +7 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
We propose how to create and manipulate one-way nonclassical light via photon blockade in rotating nonlinear devices. We refer to this effect as nonreciprocal photon blockade (PB). Specifically, we show that in a spinning Kerr resonator, PB happens when the resonator is driven in one direction but not the other. This occurs because of the {Fizeau drag,}
Huang, Ran +4 more
openaire +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

