Results 31 to 40 of about 311,597 (42)

Focused ultrasound-enabled brain tumor liquid biopsy [PDF]

, 2018
Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong, Cheng, Galen, Dunn, Gavin P., Leuthardt, Eric C., Liu, Weijun, Nazeri, Arash, Petti, Allegra A., Wang, Xiaowei, Ye, Dezhuang, Yue, Yimei, Zhu, Lifei   +10 more
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Quantitative PET imaging and modeling of molecular blood-brain barrier permeability [PDF]

Neuroimaging of blood-brain barrier permeability has been instrumental in identifying its broad involvement in neurological and systemic diseases. However, current methods evaluate the blood-brain barrier mainly as a structural barrier. Here we developed
Abdelhafez, Yasser G, Badawi, Ramsey D, Chen, Moon S, Cherry, Simon R, Chung, Kevin J, Jones, Terry, Lyo, Victoria, Medici, Valentina, Nardo, Lorenzo, Sarkar, Souvik, Spencer, Benjamin A, Tran, Quyen, Wang, Guobao   +12 more
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PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]

, 2007
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Adamson, Barreiro, Barreiro, Butcher, Carman, Carman, Carson, Celli, Christine Rampon, Cicmil, Doulet, Durieu-Trautmann, Engelhardt, Etienne, Etienne, Etienne-Manneville, Federici, Gopalakrishnan, Graesser, Gratzinger, Greenwood, Greenwood, Henshall, Hoffmann, Ilan, Jackson, Jean-Pierre Couty, John Greenwood, Kontaridis, Lacalle, Marie-Pierre Laran-Chich, Masuda, Mathilde Leveque, Millan, Muller, Newman, Newman, Patil, Pierre-Olivier Couraud, Pluskota, Reid, Rivard, Roux, Sander, Sandrine Bourdoulous, Schenkel, Schoenwaelder, Schweitzer, Shaw, Viegas, Walters, Wang, Yang, Yang   +53 more
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Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain [PDF]

, 2017
There is accumulating evidence that bumetanide, which has been used over decades as a potent loop diuretic, also exerts effects on brain disorders, including autism, neonatal seizures, and epilepsy, which are not related to its effects on the kidney but ...
Erker, Thomas, Fedrowitz, Maren, Hampel, Philip, Kaczmarek, Edith, Löscher, Wolfgang, Römermann, Kerstin, Sweet, Douglas H., Töllner, Kathrin   +7 more
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Effects of HIV and Drugs of Abuse on the Blood-Brain Barrier [PDF]

, 2016
Despite effective systemic therapy, HIV-1 infection within the brain results in neuronal degradation and neurocognitive dysfunction. This neurocognitive dysfunction is worsened in the setting of opiate abuse. The central nervous system (CNS) is protected
Hari, Gopika
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Predicting drug penetration across the blood-brain barrier: comparison of micellar liquid chromatography and immobilized artificial membrane liquid chromatography [PDF]

, 2012
Several in vitro methods have been investigated for mimicking drug penetration across the blood-brain barrier (BBB) into the central nervous system (CNS).
De Vrieze, Mike, Lynen, Frederic, Sandra, Patrick   +2 more
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Computational and in vitro studies of blast-induced blood-brain barrier disruption

, 2015
There is growing concern that blast-exposed individuals are at risk of developing neurological disorders later in life. Therefore, it is important to understand the dynamic properties of blast forces on brain cells, including the endothelial cells that ...
Banks, William A., Cook, David G., Del Razo, Mauricio J., Huber, B. Russell, Leveque, Randall J., Meabon, James S., Morofuji, Yoichi, Mourad, Pierre D., Peskind, Elaine R.   +8 more
core   +1 more source

Blood-brain carrier co-culture models to study nanoparticle penetration : focus on co-culture systems [PDF]

, 2015
The blood-brain barrier, as a physical, active transport and metabolic barrier represents the main obstacle in the treatment of central nervous system diseases.
Bocsik, Alexandra, Deli, Mária A, Hantosi, Dóra, Veszelka, Szilvia, Walter, Fruzsina   +4 more
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BLOOD-BRAIN BARRIER [PDF]

, 2010
Bainton, R., Barres, B., Daneman, R.
core   +1 more source

Mechanisms of dopaminergic neurotoxin-induced blood-brain barrier disruption [PDF]

, 2008
Blood-brain barrier disruption in Parkinson's disease and Parkinson's disease models that involve dopaminergic neurodegeneration has been minimally evaluated despite mounting evidence for its involvement.
Larsen, Niccole Jewel
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