Results 31 to 40 of about 330,080 (279)

MOESM1 of Kv1.3 channel blocker (ImKTx88) maintains bloodâ brain barrier in experimental autoimmune encephalomyelitis

, 2017
Additional file 1: Tables S1. ImKTx88 reduces clinical signs in EAE rats.
Huang, Jie, Han, Song, Sun, Qi, Yipeng Zhao, Junchen Liu, Xiaolu Yuan, Wenqian Mao, Biwen Peng, Wanhong Liu, Yin, Jun, Xiaohua He   +10 more
openaire   +1 more source

Accumulation of GD1α Ganglioside in MDA-MB-231 Breast Cancer Cells Expressing ST6GalNAc V

Molecules, 2015
α-Series gangliosides define a particular sub-class of glycosphingolipids containing sialic acid α2,6-linked to GalNAc residue that was isolated as a minor compound from the brain.
Sandy Vandermeersch, Jorick Vanbeselaere, Clément P. Delannoy, Aurore Drolez, Caroline Mysiorek, Yann Guérardel, Philippe Delannoy, Sylvain Julien   +7 more
doaj   +1 more source

MOESM1 of Accelerated differentiation of human induced pluripotent stem cells to bloodâ brain barrier endothelial cells

, 2017
Additional file 1. Additional characterization of iPSC-derived BMECsâ primary antibody and secondary antibody information, including recognized antigen, clone, vendor, and dilution, are listed in Tables S1 and S2, respectively. Immunocytochemical analysis of astrocytes and pericytes used in co-culture experiment are shown in Figure S1.
Hollmann, Emma, Bailey, Amanda, Archit Potharazu, M. Neely, Bowman, Aaron, Lippmann, Ethan   +5 more
openaire   +1 more source

Cannabinoids, Blood–Brain Barrier, and Brain Disposition

Pharmaceutics, 2020
Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory agents, anti-seizure compounds.
Fabrizio Calapai, Luigi Cardia, Emanuela Elisa Sorbara, Michele Navarra, Sebastiano Gangemi, Gioacchino Calapai, Carmen Mannucci   +6 more
doaj   +1 more source

MOESM1 of The role of mutations associated with familial neurodegenerative disorders on bloodâ brain barrier function in an iPSC model

, 2019
Additional file 1: Figure S1. Phase images of differentiation of iPSCs. Figure S2. Western blots. Figure S3. Expression of individual proteins and genes across all disease lines. Figure S4. Protein and gene expression by disease. Figure S5. Gene expression normalized to WT2 and iPS12 lines. Figure S6. Additional stains: ZO-1. Figure S7.
Katt, Moriah, Lakyn Mayo, Ellis, Shannon, Mahairaki, Vasiliki, Rothstein, Jeffrey, Linzhao Cheng, Searson, Peter   +6 more
openaire   +1 more source

Optimal acquisition and modeling parameters for accurate assessment of low K_trans blood-brain barrier permeability using dynamic contrast-enhanced MRI [PDF]

Magnetic Resonance in Medicine, 2015
To determine optimal parameters for acquisition and processing of dynamic contrast-enhanced MRI (DCE-MRI) to detect small changes in near normal low blood-brain barrier (BBB) permeability.Using a contrast-to-noise ratio metric (K-CNR) for Ktrans precision and accuracy, the effects of kinetic model selection, scan duration, temporal resolution, signal ...
Berislav V. Zlokovic, Thomas Ng, Thomas Ng, Samuel Barnes, Meng Law, Russell E. Jacobs, Axel Montagne   +6 more
openaire   +5 more sources

Additional file 1: of Mesenchymal stem cells decrease bloodâ brain barrier permeability in rats with severe acute pancreatitis

, 2019
Table of primers. (DOCX 15 kb)
Ronggui Lin, Li, Ming, Meiqin Luo, Tianhong Teng, Pan, Yu, Heguang Huang   +5 more
openaire   +1 more source

Effects of Pringle maneuver and partial hepatectomy on the pharmacokinetics and blood–brain barrier permeability of sodium fluorescein in rats

Brain Research, 2015
Liver diseases are known to affect the function of remote organs. The aim of the present study was to investigate the effects of Pringle maneuver, which results in hepatic ischemia-reperfusion (IR) injury, and partial hepatectomy (Hx) on the pharmacokinetics and brain distribution of sodium fluorescein (FL), which is a widely used marker of blood-brain
Imam H. Shaik, Mohammad K. Miah, Reza Mehvar, Reza Mehvar, Ulrich Bickel   +4 more
openaire   +4 more sources

MOESM1 of Human ES-derived MSCs correct TNF-Îą-mediated alterations in a bloodâ brain barrier model

, 2019
Additional file 1: Table S1. List qRT-PCR human primer sequences.
Ge, Shujun, Jiang, Xi, Paul, Debayon, Song, Li, Wang, Xiaofang, Pachter, Joel   +5 more
openaire   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source