Results 311 to 320 of about 966,153 (399)

Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age. [PDF]

Aging (Albany NY)
Sapkota A, Halder SK, Milner R.
europepmc   +1 more source

Kinetic Analysis of the Disposition of Hydrophilic Drugs in the Central Nervous System (CNS) : Prediction of the CNS Disposition from the Transport Properties in the Blood-Brain and Blood-Cerebrospinal Fluid Barriers

, 1994
Hiroshi Suzuki, Yuichi Sugiyama
openalex   +2 more sources

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Interaction Between Neutrophils and Elements of the Blood-Brain Barrier in the Context of Multiple Sclerosis and Ischemic Stroke. [PDF]

Int J Mol Sci
Nowaczewska-Kuchta A, Ksiazek-Winiarek D, Glabinski A.   +2 more
europepmc   +1 more source

Establishment and Dysfunction of the Blood-Brain Barrier

Cell, 2015
Zhen Zhao, Amy R. Nelson, C. Betsholtz, B. Zlokovic   +3 more
semanticscholar   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Blood-Brain Barrier Disruption in Schizophrenia: Insights, Mechanisms, and Future Directions. [PDF]

Int J Mol Sci
Zhang F, Zhang J, Wang X, Han M, Fei Y, Wang J.   +5 more
europepmc   +1 more source

Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration

Advanced Science, EarlyView.
Schematic representation of contrast agent clearance by convective bulk flow from the ventricular spaces to the subarachnoid space on the ventral aspect of the brain, or by diffusion into the parenchyma across the pia‐glia or through the semi‐permeable ependyma. Abstract Fluid and solute exchange between cerebrospinal fluid (CSF) spaces and the central
Yann Decker, Andreas Müller, Steven T. Proulx   +2 more
wiley   +1 more source

Extravasation of Borrelia burgdorferi Across the Blood-Brain Barrier is an Extremely Rare Event. [PDF]

Adv Sci (Weinh)
Wang L, Xia Z, Singh A, Murarka B, Baumgarth N, Aucott JN, Searson PC.   +6 more
europepmc   +1 more source

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

Advanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim, Minhae Cha, Hien Thi My Ong, Jung Yoo, Yu Hyun Jeon, Sang Wu Lee, Soo Yeon Oh, Min‐Jung Kang, Youngsoo Kim, So Hee Kwon   +9 more
wiley   +1 more source