Results 21 to 30 of about 2,454,570 (173)

AlphaFold2 Update and Perspectives

open access: yesBioMedInformatics, 2023
Access to the three-dimensional (3D) structural information of macromolecules is of major interest in both fundamental and applied research. Obtaining this experimental data can be complex, time consuming, and costly.
Sébastien Tourlet   +3 more
doaj   +1 more source

A Blood Bank Standardized Production of Human Platelet Lysate for Mesenchymal Stromal Cell Expansion: Proteomic Characterization and Biological Effects

open access: yesFrontiers in Cell and Developmental Biology, 2021
Human platelet lysate (hPL) is considered a valid substitute to fetal bovine serum (FBS) in the expansion of mesenchymal stromal cells (MSC), and it is commonly produced starting from intermediate side products of whole blood donations.
Andrea Bianchetti   +11 more
doaj   +1 more source

TE-YOLOF: Tiny and efficient YOLOF for blood cell detection [PDF]

open access: yesarXiv, 2021
Blood cell detection in microscopic images is an essential branch of medical image processing research. Since disease detection based on manual checking of blood cells is time-consuming and full of errors, testing of blood cells using object detectors with Deep Convolutional Neural Network can be regarded as a feasible solution. In this work, an object
arxiv  

Optimizing Access to Unrelated Donors in Canada: Re-Examining the Importance of Donor Factors on Outcomes Following Hematopoietic Cell Transplantation

open access: yesCurrent Oncology
HLA-matched allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for many patients. Unrelated HLA-matched donors are the most frequently used donor for HCT.
Gaganvir Parmar   +5 more
doaj   +1 more source

AI based analysis of red blood cells in oscillating microchannels [PDF]

open access: yesarXiv, 2023
The flow dynamics of red blood cells in vivo in blood capillaries and in vitro in microfluidic channels is complex. Cells can obtain differnet shapes such as discoid, parachute, slipper-like shapes and various intermediate states depending on flow conditions and their viscoelastic properties.
arxiv  

Palabos-npFEM: Software for the Simulation of Cellular Blood Flow (Digital Blood) [PDF]

open access: yesJournal of Open Research Software (2021), 2020
Palabos-npFEM is a computational framework for the simulation of blood flow with fully resolved constituents. The software resolves the trajectories and deformed state of blood cells, such as red blood cells and platelets, and the complex interaction between them. The tool combines the lattice Boltzmann solver Palabos for the simulation of blood plasma
arxiv   +1 more source

Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation: A Pre-Clinical Perspective

open access: yesCurrent Oncology
Hematopoietic stem-cell (HSC) transplantation (HSCT) is used to treat various hematologic disorders. Use of genetically modified mouse models of hematopoietic cell transplantation has been critical in our fundamental understanding of HSC biology and in ...
Tanvir Hasan   +5 more
doaj   +1 more source

Continuous Magnetophoretic Separation of Blood Cells from Plasma at the Microscale [PDF]

open access: yes, 2007
We present a method for the direct and continuous separation of red and white blood cells from plasma at the microscale. The method is implemented in a microfluidic system with magnetic functionality. The fluidic structure within the microsystem consists of an inlet and a single microfluidic channel with multiple outlets.
arxiv   +1 more source

The Effects of ATO on Mitochondria Apoptosis Pathway Genes Expression in APL Cell Line

open access: yesAsian Pacific Journal of Cancer Biology, 2016
Purpose and Background: Acute promyelocystic leukemia is the most malignant acute leukemia that leads to death in few weeks. It constitutes 10-15% of acute myelocystic leukemia.
Maede Sharifizadeh   +7 more
doaj   +1 more source

Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment

open access: yesJournal of Translational Medicine, 2023
Background Wharton’s Jelly (WJ) Mesenchymal Stromal Cells (MSC) have emerged as an attractive allogeneic therapy for a number of indications, except for bone-related conditions requiring new tissue formation.
Raquel Cabrera-Pérez   +5 more
doaj   +1 more source

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