Results 21 to 30 of about 4,387,004 (356)

Immunotherapies targeting GPRC5D in relapsed or refractory multiple myeloma: latest updates from 2022 ASH Annual Meeting

Journal of Hematology & Oncology, 2023
B cell maturation antigen (BCMA)-targeted immunotherapy has shown unprecedented results in the treatment of relapsed or refractory (R/R) multiple myeloma (MM).
Jieyun Xia, Zhenyu Li, Kailin Xu
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A combination of pre-infusion serum ferritin, CRP and IL-6 predicts outcome in relapsed/refractory multiple myeloma patients treated with CAR-T cells

Frontiers in Immunology, 2023
BackgroundChimeric antigen receptor - T (CAR-T) cell therapy has shown remarkable efficacy in patients with relapsed/refractory multiple myeloma (R/R MM).
Yang Liu, Yang Liu, Yang Liu, Xingxing Jie, Xingxing Jie, Xingxing Jie, Li Nian, Li Nian, Li Nian, Ying Wang, Ying Wang, Ying Wang, Congyue Wang, Congyue Wang, Congyue Wang, Jin Ma, Jin Ma, Jin Ma, Jingjing Jiang, Jingjing Jiang, Jingjing Jiang, Qingyun Wu, Qingyun Wu, Qingyun Wu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wei Chen, Wei Chen, Wei Chen, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Ming Shi, Hai Cheng, Hai Cheng, Hai Cheng, Feng Zhu, Feng Zhu, Feng Zhu, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Chong Chen, Chong Chen, Chong Chen, Kailin Xu, Kailin Xu, Kailin Xu, Zhenyu Li, Zhenyu Li, Zhenyu Li   +57 more
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Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]

, 2016
Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya, Iguchi, Masaharu, Ishizaki, Takeshi, Kadowaki, Maiko, Kato, Ryo, Mizuno, Shiro, Nakagawa, Ken, Oikawa, Taku, Osanai, Kazuhiro, Shiozaki, Kohei, Toga, Hirohisa, Voelkel, Norbert F   +11 more
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Drosophila blood cell chemotaxis

Current Opinion in Cell Biology, 2014
Drosophila melanogaster contains a population of blood cells called hemocytes that represent the functional equivalent of vertebrate macrophages. These cells undergo directed migrations to disperse during development and reach sites of tissue damage or altered self.
Evans, I.R., Wood, W.
openaire   +4 more sources

EPC infusion ameliorates acute graft-versus-host disease-related endothelial injury after allogeneic bone marrow transplantation

Frontiers in Immunology, 2022
IntroductionGraft-versus-host disease (GVHD) damages vascular endothelium. Endothelial progenitor cell (EPC) can differentiate to endothelial cell and promote angiogenesis, but its role in endothelial damage in GVHD is unclear.MethodsIn this study, we ...
Weiwei Wang, Weiwei Wang, Weiwei Wang, Yali Ye, Yali Ye, Yali Ye, Yuwei Du, Yuwei Du, Yuwei Du, Zhengqing Xu, Zhengqing Xu, Zhengqing Xu, Ke Yuan, Ke Yuan, Ke Yuan, Yizhou Wang, Yizhou Wang, Yizhou Wang, Seyram Yao Adzraku, Seyram Yao Adzraku, Seyram Yao Adzraku, Yue Li, Yue Li, Yue Li, Kailin Xu, Kailin Xu, Kailin Xu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wen Ju, Wen Ju, Wen Ju, Lingyu Zeng, Lingyu Zeng, Lingyu Zeng   +35 more
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Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]

, 2018
The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A, Lee, Abraham P, Lee, Do-Hyun, Li, Xuan, Ma, Ning   +4 more
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A same‐day assay predicts apoptotic response to combined BCL‐2 and MCL‐1 BH3‐mimetic targeting in multiple myeloma cells

eJHaem, 2021
Recent advances in treatment options for multiple myeloma (MM) have positive impact on patient survival. However, there is a short fall of rapid and reliable assays that can predict patient response to novel agents.
Martin Grundy, Firas Al‐Kaisi, Joanna Cull, Cathy Williams, Dean Smith, Claire H. Seedhouse   +5 more
doaj   +1 more source

Two-photon imaging of cancer cell extravasation in live mice [PDF]

, 2011
MDA-MB-231 breast cancer cells were engineered to express cytoplasmic paxillin-GFP and nuclear H2B-mCherry. In order to image extravasation, the cancer cells were injected in the blood stream of nude mice.
Aguilar, Jose S, Digman, Michelle A, Gratton, Enrico, Hoffman, Robert M, Suetsugu, Atsushi   +4 more
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Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. [PDF]

, 2017
The gastrointestinal mucosa is an important site of HIV acquisition, viral replication, and pathogenesis. Immune cells in mucosal tissues frequently differ in phenotype and function from their non-mucosal counterparts.
Critchfield, JW, Deeks, SG, Ganesh, A, Hecht, FM, Hunt, PW, Kiniry, BE, Shacklett, BL, Somsouk, M   +7 more
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Long-Term Suppression of Circulating Proinflammatory Cytokines in Multiple Sclerosis Patients Following Autologous Haematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2022
Autologous haematopoietic stem cell transplantation (AHSCT) is a therapeutic option for haematological malignancies, such as non-Hodgkin’s lymphoma (NHL), and more recently, for autoimmune diseases, such as treatment-refractory multiple sclerosis (MS ...
Kevin Hendrawan, Kevin Hendrawan, Melissa L. M. Khoo, Melissa L. M. Khoo, Malini Visweswaran, Malini Visweswaran, Jennifer C. Massey, Jennifer C. Massey, Jennifer C. Massey, Jennifer C. Massey, Barbara Withers, Barbara Withers, Barbara Withers, Ian Sutton, Ian Sutton, Ian Sutton, David D. F. Ma, David D. F. Ma, David D. F. Ma, John J. Moore, John J. Moore, John J. Moore   +21 more
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