Results 191 to 200 of about 484,763 (358)

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Oral health and quality of life in children with blood coagulation disorders and hemoglobinopathies. A cross-sectional study. [PDF]

J Family Med Prim Care
Santhosh VC, Mahajan A, Manas A, Pawar M, Gupta S.   +4 more
europepmc   +1 more source

Hearing Loss and Blood Coagulation Disorders: A Review. [PDF]

Hematol Rep, 2023
Corazzi V, Migliorelli A, Bianchini C, Pelucchi S, Ciorba A.   +4 more
europepmc   +1 more source

Blood coagulation alterations over the first 10 days after severe burn injury

, 2021
Jeanne M. Barbier, Marina Verçoza Viana, Olivier Pantet, Lorenzo Alberio, Mette M. Berger   +4 more
openalex   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

An Amplitude Analysis-Based Magnetoelastic Biosensing Method for Quantifying Blood Coagulation. [PDF]

Biosensors (Basel)
Chen X, Wang Q, Deng J, Hu N, Liao Y, Yang J.   +5 more
europepmc   +1 more source

Investigation on the mechanisms of action of aprotinin in cardiac surgery [PDF]

, 1991
Baranky, A., Dietrich, W., Friedel, N., Hetzer, P., Jochum, Marianne, Richter, J. A., Royston, D., Spannagl, Michael, Wendt, P.   +8 more
core   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Reversible High-Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation. [PDF]

Adv Sci (Weinh)
Shi C, He M, Chen H, Wei X, Xiao L, Shang X, Shi Y, Wang Q, Yu L, Fan J.   +9 more
europepmc   +1 more source

Agonal Thrombus at Necropsy-A Third Category of Blood Coagulation in Domestic Carnivores. [PDF]

Life (Basel), 2023
Tiu RE, Rizac RI, Nicolae GL, Turbatu RM, Ciobotaru-Pirvu E.   +4 more
europepmc   +1 more source