Results 231 to 240 of about 5,111,387 (310)

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Exploratory Analysis of Factors Associated With the Recovery of Erectile Dysfunction After Rectal Cancer Surgery (Sub‐Analysis of LANDMARC Trial)

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Erectile dysfunction (ErD) is an important complication after rectal cancer surgery, however a substantial proportion of patients experience functional recovery over time. Evidence regarding which patients are more likely to recover remains limited.
Ryosuke Mizuno, Koya Hida, Masakatsu Numata, Takashi Sakamoto, Kazutaka Obama, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Mayumi Ozawa, Masanori Hotchi, Daisuke Yamamoto, Suguru Hasegawa, Masashi Miguchi, Shinobu Ohnuma, Tomohiro Yamaguchi, Tomonori Akagi, Yusuke Kinugasa, Shigeki Yamaguchi, Hiroyasu Kagawa, Masahiko Watanabe, Takeshi Naitoh, Ichiro Takemasa   +21 more
wiley   +1 more source

Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces. [PDF]

J Thromb Haemost
Avery NG, Young IR, Lu S, Vaughan JD, Korus PS, Richardson TN, Childers KC, Smirnov SL, Spiegel PC.   +8 more
europepmc   +1 more source

Prediction of Long‐Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi, Kenichiro Araki, Norio Kubo, Takamichi Igarashi, Shunsuke Kawai, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Ken Shirabe   +8 more
wiley   +1 more source

Atomistic Mechanism of Lipid Membrane Binding for Blood Coagulation Factor VIII with Molecular Dynamics Simulations on a Microsecond Time Scale. [PDF]

J Phys Chem B
Avery NG, Childers KC, McCarty J, Spiegel PC.   +3 more
europepmc   +1 more source

Comparison of the therapeutic effects in patients with venous leg ulcers treated with routine therapy supplemented by topical hyperbaric oxygen therapy or routine therapy only, basing on the measurement of selected inflammatory markers and blood coagulation parameters: a retrospective study. [PDF]

Postepy Dermatol Alergol
Pasek J, Szajkowski S, Cieślar G.
europepmc   +1 more source

Biochemical Approach to Poly(Lactide)-Copper Composite-Impact on Blood Coagulation Processes. [PDF]

Materials (Basel)
Mrozińska Z, Kudzin MH, Ponczek MB, Kaczmarek A, Król P, Lisiak-Kucińska A, Żyłła R, Walawska A.   +7 more
europepmc   +1 more source

Blood coagulation factor IX: structural insights impacting hemophilia B therapy.

Blood
Bos MHA, van Diest RE, Monroe DM.
europepmc   +1 more source

The in vitro cross-reactivity and blood coagulation potential of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A. [PDF]

Int J Hematol
Takeyama M, Sasai K, Miyaguchi Y, Ogiwara K, Furukawa S, Shimonishi N, Nakajima Y, Ueda H, Nogami K.   +8 more
europepmc   +1 more source

Blood Coagulation-Inspired Fibrin Hydrogel for Portable Detection of Thrombin Based on Personal Glucometer. [PDF]

Biosensors (Basel)
Yang DN, Wu SY, Deng HY, Zhang H, Shi S, Geng S.   +5 more
europepmc   +1 more source