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The clinical effect of endoscopic and open surgery in the treatment of thyroid cancer and their effect on the blood coagulation state: a comparative study. [PDF]
Ann Surg Treat ResXu Q, Zhu L, Chen W, Peng W.
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Lancet, The, 2000
Under normal circumstances, the coagulation system is balanced in favour of anticoagulation. Thrombin is the key effector enzyme of the clotting cascade. Antagonists of vitamin K inhibit a vitamin-K-dependent post-translational modification of several coagulation proteins, which is required for these proteins to attain a phospholipid-binding ...
B Dahlbäck
exaly +3 more sources
Under normal circumstances, the coagulation system is balanced in favour of anticoagulation. Thrombin is the key effector enzyme of the clotting cascade. Antagonists of vitamin K inhibit a vitamin-K-dependent post-translational modification of several coagulation proteins, which is required for these proteins to attain a phospholipid-binding ...
B Dahlbäck
exaly +3 more sources
Biochemistry (Moscow), 2002
The process of tissue factor initiated blood coagulation is discussed. Reactions of the blood coagulation cascade are propagated by complex enzymes containing a vitamin K-dependent serine protease and an accessory cofactor protein that are assembled on a membrane surface in a calcium-dependent manner.
S. Butenas, K. G. Mann, null Butenas
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The process of tissue factor initiated blood coagulation is discussed. Reactions of the blood coagulation cascade are propagated by complex enzymes containing a vitamin K-dependent serine protease and an accessory cofactor protein that are assembled on a membrane surface in a calcium-dependent manner.
S. Butenas, K. G. Mann, null Butenas
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Biomaterials, 2019
Effective bleeding control and wound healing are very important and can be life saving. However, traditional wound dressings with structural deficiencies are not effective in controlling bleeding and promoting the regeneration of functional tissues.
Kexin Zhang +8 more
semanticscholar +1 more source
Effective bleeding control and wound healing are very important and can be life saving. However, traditional wound dressings with structural deficiencies are not effective in controlling bleeding and promoting the regeneration of functional tissues.
Kexin Zhang +8 more
semanticscholar +1 more source
Microplastic particles in human blood and their association with coagulation markers
Scientific ReportsRecent studies have indicated potential health risks associated with microplastics (MPs) exposure, including alterations in blood coagulation homeostasis.
Dong-Wook Lee +8 more
semanticscholar +1 more source
Best Practice & Research Clinical Obstetrics & Gynaecology, 2003
Blood coagulation can be initiated by two pathways: the extrinsic pathway, which is triggered by release of tissue factor from the site of injury, and the intrinsic system, which is stimulated by contact with a negatively charged surface. Following initial triggering, a series of serine proteases are sequentially activated, culminating in the formation
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Blood coagulation can be initiated by two pathways: the extrinsic pathway, which is triggered by release of tissue factor from the site of injury, and the intrinsic system, which is stimulated by contact with a negatively charged surface. Following initial triggering, a series of serine proteases are sequentially activated, culminating in the formation
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American Journal of Physiology-Legacy Content, 1962
Blood coagulation systems in cyclostome, elasmobranch, and teleost fish were studied and compared. The plasma of all these fish contained a fibrinogen molecule, capable of being clotted by human thrombin, and a prothrombin molecule, capable of being converted into thrombin which could hydrolyze p-tosyl l-arginine methyl ester. The prothrombin activity
Russell F, Doolittle +1 more
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Blood coagulation systems in cyclostome, elasmobranch, and teleost fish were studied and compared. The plasma of all these fish contained a fibrinogen molecule, capable of being clotted by human thrombin, and a prothrombin molecule, capable of being converted into thrombin which could hydrolyze p-tosyl l-arginine methyl ester. The prothrombin activity
Russell F, Doolittle +1 more
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Thrombosis and Haemostasis, 1967
SummaryInvestigations were performed on the effects of elinin on blood coagulation. It was found that elinin exerts significant anticoagulant activity. This was demonstrated by an one-stage re calcification test, prothrombin consumption, thromboplastin and thrombin generation.
N, Vulpis, G, Vulpis, C, Santoro
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SummaryInvestigations were performed on the effects of elinin on blood coagulation. It was found that elinin exerts significant anticoagulant activity. This was demonstrated by an one-stage re calcification test, prothrombin consumption, thromboplastin and thrombin generation.
N, Vulpis, G, Vulpis, C, Santoro
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Blood Coagulation & Fibrinolysis, 2000
We have used three models to study the process of tissue factor-initiated blood coagulation. These are: synthetic 'plasma' mixtures prepared with the proteins and membranes involved in the reaction and its regulation; mathematical models based on the reaction kinetics, binding constants and stoichiometries of individual procoagulant and inhibitor ...
Butenas, S. +4 more
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We have used three models to study the process of tissue factor-initiated blood coagulation. These are: synthetic 'plasma' mixtures prepared with the proteins and membranes involved in the reaction and its regulation; mathematical models based on the reaction kinetics, binding constants and stoichiometries of individual procoagulant and inhibitor ...
Butenas, S. +4 more
openaire +2 more sources
Journal of Pediatric Oncology Nursing, 2007
Although the concept of the coagulation cascade represented a significant advance in the understanding of coagulation and served for many years as a useful model, more recent clinical and experimental observations demonstrate that the cascade/waterfall hypothesis does not fully and completely reflect the events of hemostasis in vivo.
James P, Riddel +3 more
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Although the concept of the coagulation cascade represented a significant advance in the understanding of coagulation and served for many years as a useful model, more recent clinical and experimental observations demonstrate that the cascade/waterfall hypothesis does not fully and completely reflect the events of hemostasis in vivo.
James P, Riddel +3 more
openaire +2 more sources