Results 251 to 260 of about 5,111,387 (310)
Some of the next articles are maybe not open access.
Current Opinion in Hematology, 2004
The biochemistry of blood coagulation has been well defined over the past 50 years. Although much is known about the sequence of the proteolytic cascade and its regulation in the pathway to fibrin generation, many important questions remain unsolved about the mechanism of initiation and the structure of the protein complexes that form during blood ...
Monica, Schenone +2 more
openaire +2 more sources
The biochemistry of blood coagulation has been well defined over the past 50 years. Although much is known about the sequence of the proteolytic cascade and its regulation in the pathway to fibrin generation, many important questions remain unsolved about the mechanism of initiation and the structure of the protein complexes that form during blood ...
Monica, Schenone +2 more
openaire +2 more sources
Blood Coagulation and Coagulation Tests
Medical Clinics of North America, 1984The hemostatic mechanism has evolved to provide efficient protection from traumatic blood loss and yet maintain the blood in a fluid state in the circulation as a whole. Recent advances in biochemistry have provided both detailed understanding of hemostasis and clinically useful coagulation assays to exploit this understanding.
openaire +2 more sources
Biorheology, 1996
There have been a number of investigations on coagulation reactions of blood as well as on coagulation factors including fibrinogen and thrombin. With the progress of clotting, the viscosity and rigidity of blood increase, facts related to the clot structure of fibrin.
openaire +2 more sources
There have been a number of investigations on coagulation reactions of blood as well as on coagulation factors including fibrinogen and thrombin. With the progress of clotting, the viscosity and rigidity of blood increase, facts related to the clot structure of fibrin.
openaire +2 more sources
Blood Cells, Molecules, and Diseases, 2006
Our research aims to provide quantitatively transparent, biologically realistic descriptions of the processes involved in hemostasis which will permit predictions of the behavior of the coagulation system in normal and pathologic states. We use four models of coagulation: (1) numerical approximations of the tissue factor (Tf) pathway of thrombin ...
Kenneth G, Mann +3 more
openaire +2 more sources
Our research aims to provide quantitatively transparent, biologically realistic descriptions of the processes involved in hemostasis which will permit predictions of the behavior of the coagulation system in normal and pathologic states. We use four models of coagulation: (1) numerical approximations of the tissue factor (Tf) pathway of thrombin ...
Kenneth G, Mann +3 more
openaire +2 more sources
Clinics in Laboratory Medicine, 1996
This article reviews the current understanding of coagulation and its role in overall hemostasis. Also provided is an overview of current screening and specialized tests of coagulation.
openaire +2 more sources
This article reviews the current understanding of coagulation and its role in overall hemostasis. Also provided is an overview of current screening and specialized tests of coagulation.
openaire +2 more sources
The kinetics of blood coagulation
The Bulletin of Mathematical Biophysics, 1948The kinetics of the blood coagulation system have been formulated and an expression obtained for the “prothrombin time” in terms of the concentrations of the components of the system. A linear plot of data obtained from plasma dilution curves gives the values of the parameters of the system, and yields a mathematical method of comparing relative ...
openaire +2 more sources
The Coagulation of Blood and Hemostasis
Annual Review of Physiology, 1950Since the number of papers on coagulation has greatly in creased, the reviewer, in order to avoid merely cataloging them with telegraphic brevity, was compelled to select mainly those which contribute specifically to the physiology of blood clotting.
openaire +2 more sources
Regulation of blood coagulation
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000The protein C anticoagulant pathway converts the coagulation signal generated by thrombin into an anticoagulant response through the activation of protein C by the thrombin-thrombomodulin (TM) complex. The activated protein C (APC) thus formed interacts with protein S to inactivate two critical coagulation cofactors, factors Va and VIIIa, thereby ...
openaire +2 more sources
Blood coagulation in glomerulonephritis
International Urology and Nephrology, 1986Different parameters of coagulation were studied in 71 patients with glomerulonephritis. In comparison with normal subjects they had lower platelet counts, lower adhesion index and decreased aggregation, decreased partial thromboplastin time (46.4 per cent of patients), increased reptilase time (47.8 per cent) and other disorders. Plasma fibrin monomer
N, Belovezhdov, R, Robeva, V, Genova
openaire +2 more sources
Physiology of Blood Coagulation
Haemostasis, 2009Blood coagulation forms part of an integrated series of haemostatic reactions, involving plasma, platelet, and vascular components. Platelets adhere to damaged endothelium or to subendothelium under the influence of adhesive proteins, and when activated they aggregate and expose binding sites for coagulation factors.
openaire +2 more sources