Results 261 to 270 of about 4,437,076 (344)

Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis

open access: yesAdvanced Science, EarlyView.
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang   +14 more
wiley   +1 more source

Enhancing Chemotherapy‐Related Immune Responses via Bioorthogonal Metabolic Engineering‐Driven Tumor Exosomes Elimination

open access: yesAdvanced Science, EarlyView.
In this work, a novel strategy named bioorthogonal reaction‐driven exosome elimination (Biordee) strategy was developed to inhibit chemotherapy‐associated breast cancer metastasis and enhance the immune response. Biordee possessed the capacity of in‐situ editing tumor‐derived exosomes (TExo) with IgG Fc and promoted macrophage phagocytosis of ...
Wentao Zhang   +6 more
wiley   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

Dynamic Imaging of Blood Coagulation Within the Hematoma of Patients With Acute Hemorrhagic Stroke. [PDF]

open access: yesStroke
Haque ME   +20 more
europepmc   +1 more source

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