Results 101 to 110 of about 186,764 (349)

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source

FIBRINOLYSIS: MODERN VIEW, PATHOLOGY, DIAGNOSTICS

Байкальский медицинский журнал
Relevance. Fibrinolysis is an important and integral part of the hemostasis system. Acting in parallel and together, the blood coagulation and fibrinolysis systems protect the body from excessive thrombus formation and vascular occlusion, on the one hand,
Lyudmila O. Gutsol, Irina E. Egorova, Igor Zh. Seminsky, Evgenia V. Guzovskaiia, Svetlana N. Serebrennikova, Lyudmila A. Dmitrieva   +5 more
doaj   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Precision infusion of cryoprecipitate in rare bleeding disorders

Zhongguo shuxue zazhi
The coagulation factors in cryoprecipitate are mainly coagulation factor Ⅷ, fibrinogen, von Willebrand factor (VWF), and coagulation factor ⅩⅢ. This article provides different treatment dosages and plans for different patients with rare coagulation ...
SUN Changkui, WANG Tiantian, WANG Jie, FANG Yunhai   +3 more
doaj   +1 more source

Severe Postpartum Coagulopathy Without Haemorrhage: A Case Report

Acta Médica Portuguesa, 2018
Postpartum haemorrhage is an important health issue worldwide, and it can be caused by uterine atony, retained placental tissue, trauma or coagulation disorders. Although coagulopathy represents a rare cause, it is a significant contributor to postpartum
Muriel Lérias-Cambeiro, Anabela Rodrigues, Inês Taborda, Filipa Lança   +3 more
doaj   +1 more source

Warfarin-Induced Hemorrhagic Pseudocyst in the Pelvic of a Woman with an Inherited Disorder of Blood Coagulation, Complicated by Pelvic Bone Pseudoxanthoma Mimicking Erdheim-Chester Disease [PDF]

, 2007
Z Kinkor, K. Koudela, K. Koudela, F Havlícek, J Koudelová   +4 more
openalex   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Hemostazni sistem i ishemijska bolest mozga (opšti aspekt) [PDF]

Vojnosanitetski Pregled, 2002
Raičević Ranko, Jovičić Aco, Mandić-Radić Slavka, Đorđević Dragana   +3 more
doaj   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Correction of Disorders in Tissue Perfusion, Blood Coagulation and Fibrinolysis with Orbita Apparatus on Terahertz Waves of Cell Metabolites [PDF]

, 2013
Vaycheslav Kirichuk
openalex   +2 more sources