Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study. [PDF]
, 2016 Background. Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid (TXA) has the potential to reduce bleeding and a large randomized placebo controlled trial of its effect in women with PPH (The WOMAN trial) is underway.
Beaumont, Danielle +10 more
core +2 more sources
Respiratory antiviral immunity and immunobiotics: Beneficial effects on inflammation-coagulation interaction during influenza virus infection [PDF]
, 2016 Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a high degree of morbidity and mortality, especially in high-risk populations such as infants, elderly, and immunocompromised hosts.
Alvarez, Gladis Susana +3 more
core +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2023 Cerebral venous sinus thrombosis (CVST) has become a rare but potentially life-threatening condition in perinatal women. Early and rapid identification of CVST in pregnant women is a challenge for frontline clinical workers.
Ming Li MS +6 more
doaj +1 more source
How we treat bleeding associated with direct oral anticoagulants [PDF]
, 2016 Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo +4 more
core +1 more source
EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis. [PDF]
PLoS ONE, 2016 EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7, a causative agent of diarrhea-associated Hemolytic Uremic Syndrome (D+HUS).
Kevin H M Kuo +9 more
doaj +1 more source
Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter season [PDF]
, 2010 Background and Objective Air temperature changes are associated with increased cardiovascular and respiratory risk, but the roles of inflammatory and coagulation markers are not well understood.
Breitner, Susanne +8 more
core +1 more source
Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid [PDF]
Pediatric Emergency Medicine JournalFactor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic ...
Kyu Hwa Jeong +2 more
doaj +1 more source
Clotting Phenomena at the Blood-Polymer Interface and Development of Blood Compatible Polymeric Surfaces [PDF]
, 1972 In the past two decades many attempts have been made to relate surface and interfacial parameters with the blood compatibility of polymeric surfaces. It is however doubtful if by a single parameter the behaviour of blood on a surface can be predicted ...
Bantjes, Adriaan
core +3 more sources
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021 Background Aggressive fluid management and other external factors may lead to hypothermia, acidosis and hemodilution (defined as Lethal Triad, LT) contributing to a trauma-induced coagulopathy (TIC) that worsens patients’ outcomes.
Julia K. Böhm +5 more
doaj +1 more source
The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]
, 2017 Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo +6 more
core +1 more source