Results 31 to 40 of about 225,640 (263)
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Perioperative transfusion strategies for patients with rare coagulation factor deficiency
Objective To discuss the perioperative blood transfusion strategy of patients with hereditary coagulation factor deficiency through the perioperative blood coagulation management of a patient with coagulation factor Ⅺ deficiency and hemangioma of knee ...
SUO Zhengxin +3 more
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Association of Plasma Fibrinogen and Thromboelastography With Blood Loss in Complex Cardiac Surgery
Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available.
Eline A. Vlot MD +6 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
PROTHROMBIN AND ANTITHROMBIN FACTORS IN THE COAGULATION OF BLOOD [PDF]
Few have studied the prothrombin and antithrombin factors of coagulation of the blood in human cases. Howell 1 devised methods to study these factors and has reported a deficiency of prothrombin in hemophilia with relative excess of antithrombin, a diminution of antithrombin in cases of spontaneous thrombosis and no abnormality in the cases of purpura ...
openaire +2 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Macrophages produce blood coagulation factors
2 .l . Preparation of macrophage cultures Macrophages were obtained from hybrid C3DZF1 (C3H/Tifo9 X DBA/2 d) mice by peritoneal washing with phosphate-buffered saline without anticoagulant. Cells were routinely cultured in MEM (minimum essential medium with Earle’s salts, Gibco Bio-cult, Paisley, Scotland) supplemented with 0.05% (w/v) heat inactivated
Østerud, Bjarne +2 more
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

