Results 31 to 40 of about 9,520,726 (283)
The Tissue Factor Requirement in Blood Coagulation [PDF]
Journal of Biological Chemistry, 2005 Formation of thrombin is triggered when membrane-localized tissue factor (TF) is exposed to blood. In closed models of this process, thrombin formation displays an initiation phase (low rates of thrombin production cause platelet activation and fibrinogen clotting), a propagation phase (>95% of thrombin production occurs), and a termination phase ...
Thomas, Orfeo +3 more
openaire +2 more sources
Вестник хирургии имени И.И. Грекова, 2021 The OBJECTIVE was to study the features of changes in the blood coagulation system that contribute to the development of postoperative complications in patients depending on the stage of non-tumor mechanical jaundice at admission.METHODS AND MATERIALS. A
V. E. Fedorov +4 more
doaj +1 more source
Вестник анестезиологии и реаниматологии, 2020 Massive obstetric hemorrhage is one of the most threatening complications of pregnancy, delivery and early postpartum period, which are part of the triad of leading causes of maternal mortality both in the world and in the Russian Federation.
A. V. Kuligin +2 more
doaj +1 more source
EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis. [PDF]
PLoS ONE, 2016 EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7, a causative agent of diarrhea-associated Hemolytic Uremic Syndrome (D+HUS).
Kevin H M Kuo +9 more
doaj +1 more source
Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid [PDF]
Pediatric Emergency Medicine JournalFactor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic ...
Kyu Hwa Jeong +2 more
doaj +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2023 Cerebral venous sinus thrombosis (CVST) has become a rare but potentially life-threatening condition in perinatal women. Early and rapid identification of CVST in pregnant women is a challenge for frontline clinical workers.
Ming Li MS +6 more
doaj +1 more source
It Is Written in the Clot: Coagulation Assessment in Severe Burn Injury
European Burn JournalBackground: Coagulopathy in severe burn injury is associated with complications and mortality. Methods: We compared 3 tests (EXTEM, INTEM, FIBTEM) of rotational thromboelastometry (ROTEM), a viscoelastic coagulation assay (VCA), with conventional ...
Eirini Nikolaidou +7 more
doaj +1 more source
Impaired thrombin generation as a reproducible feature of bleeding disorder of unknown cause
Research and Practice in Thrombosis and HaemostasisBackground: Thrombin generation (TG) has previously been investigated in patients with bleeding disorder of unknown cause (BDUC) with discrepant results.
Tim Dreier +6 more
doaj +1 more source
What role do coagulation disorders play in the pathogenesis of leptospirosis? [PDF]
, 2007 Leptospirosis is a zoonosis of worldwide distribution, spread by the urine of infected animals. It is a major public health problem, especially in developing countries, where circumstances for transmission are most favourable. The clinical picture varies
de Kruif, MD +9 more
core +1 more source
Changes in Blood Viscosity With Synthetic Protease Inhibitors
Journal of Pharmacological Sciences, 2003 We examined the effects on whole blood viscosity and coagulation time of various dosages of the synthetic low-molecular protease inhibitors gabexate mesilate and nafamostat mesilate with an oscillation-type viscometer.
Masahito Hitosugi +6 more
doaj +1 more source