Results 51 to 60 of about 9,520,726 (283)
Macrophages produce blood coagulation factors
FEBS Letters, 1980 2 .l . Preparation of macrophage cultures Macrophages were obtained from hybrid C3DZF1 (C3H/Tifo9 X DBA/2 d) mice by peritoneal washing with phosphate-buffered saline without anticoagulant. Cells were routinely cultured in MEM (minimum essential medium with Earle’s salts, Gibco Bio-cult, Paisley, Scotland) supplemented with 0.05% (w/v) heat inactivated
Østerud, Bjarne +2 more
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Perioperative transfusion strategies for patients with rare coagulation factor deficiency
Zhongguo shuxue zazhiObjective To discuss the perioperative blood transfusion strategy of patients with hereditary coagulation factor deficiency through the perioperative blood coagulation management of a patient with coagulation factor Ⅺ deficiency and hemangioma of knee ...
SUO Zhengxin +3 more
doaj +1 more source
The carboxyl-terminal region of coagulation factors: role in biosynthesis and function of FVII and FX [PDF]
, 2011 -BACKGROUND- Factor VII (FVII), factor IX (FIX), factor X (FX) and protein C (PC), belonging to the family of coagulation vitamin K-dependent serine proteases, share high sequence and structural homology at the gene and protein level.
Branchini, Alessio
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]
, 2007 Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias +11 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Association of Plasma Fibrinogen and Thromboelastography With Blood Loss in Complex Cardiac Surgery
Clinical and Applied Thrombosis/Hemostasis, 2021 Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available.
Eline A. Vlot MD +6 more
doaj +1 more source
Haemostatic studies in subarachnoid haemorrhage. [PDF]
, 2005 Object. The primary objective of this thesis was to establish the pattern of change in haemostatic systems in patients following a subarachnoid haemorrhage (SAH).
McEvoy, A.W., McEvoy, Andrew William
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source