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Blood coagulation factor VIII: An overview
Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be ...
G M, Bhopale, R K, Nanda
openaire +2 more sources
Background Aggressive fluid management and other external factors may lead to hypothermia, acidosis and hemodilution (defined as Lethal Triad, LT) contributing to a trauma-induced coagulopathy (TIC) that worsens patients’ outcomes.
Julia K. Böhm +5 more
doaj +1 more source
In blood coagulation, circulating platelets and coagulation factors are crucial for the primary process because thrombi are generated by fibrin clotting with fibrinogen, thrombin, FXIIIa, and platelet activation.
Jun-Hui Choi, Seung Kim
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THE REGULATORY ROLE OF COAGULATION FACTORS ON ARTERIAL FUNCTION
The coagulation takes place in the physiological system of hemostasis. Hemostasis is known to be disturbed in many diseases leading to hemorrhages or thrombosis.
Jeremy Lagrange
doaj +1 more source
Responses of some blood coagulation factors in recovery period after interval and continuous efforts for swimmers [PDF]
تحددت مشكلة البحث في دراسة استجابات بعض عوامل تخثر الدم في فترة استعادة الشفاء بعد الجهدين الفتري والمستمر لدى السباحين. وهدف البحث إلى الكشف عن استجابات بعض عوامل تخثر الدم في فترة الاستشفاء بعد الجهد الفتري والمستمر وفي فترة الاستشفاء(1) ساعة بعد ...
Nashwan I. Abdullah
doaj +1 more source
Molecular bases of the modulation of coagulation factor levels [PDF]
The maintenance of blood uidity within the vascular system is ensured by the balance between procoagulant and anticoagulant components. Hemostasis and blood coagulation are processes regulated by a complex network of interactions, involving plasma ...
Caruso, Pierpaolo
core
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Introduction The thrombin generation (TG) test is a global hemostasis assay sensitive to procoagulant conditions. However, some TG assays may underestimate elevated TG when the thrombin fluorogenic substrate is depleted or fluorescence is attenuated by ...
William C. Chang +4 more
doaj +1 more source
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Management of a Patient with Bombay Blood Group and Chronic Liver Disease with Subdural Hematoma
The Bombay blood group is an extremely rare entity within the conventional ABO blood grouping system. End-stage liver disease also presents with myriad disorders of coagulation due to impaired synthesis and dysfunction of clotting factors, which ...
Siddharth Chavali +3 more
doaj +1 more source

