Results 21 to 30 of about 225,640 (263)

Impaired thrombin generation as a reproducible feature of bleeding disorder of unknown cause

Research and Practice in Thrombosis and Haemostasis
Background: Thrombin generation (TG) has previously been investigated in patients with bleeding disorder of unknown cause (BDUC) with discrepant results.
Tim Dreier, Dino Mehic, Justin Oosterlee, Helmut Haslacher, Cihan Ay, Ingrid Pabinger, Johanna Gebhart   +6 more
doaj   +1 more source

Changes in Blood Viscosity With Synthetic Protease Inhibitors

Journal of Pharmacological Sciences, 2003
We examined the effects on whole blood viscosity and coagulation time of various dosages of the synthetic low-molecular protease inhibitors gabexate mesilate and nafamostat mesilate with an oscillation-type viscometer.
Masahito Hitosugi, Munehiro Niwa, Tomoyoshi Takahashi, Akira Kurosu, Hirohisa Nihei, Toshiaki Nagai, Shogo Tokudome   +6 more
doaj   +1 more source

In Vitro Antithrombotic, Hematological Toxicity, and Inhibitor Studies of Protocatechuic, Isovanillic, and p-Hydroxybenzoic Acids from Maclura tricuspidata (Carr.) Bur

Molecules, 2022
In blood coagulation, circulating platelets and coagulation factors are crucial for the primary process because thrombi are generated by fibrin clotting with fibrinogen, thrombin, FXIIIa, and platelet activation.
Jun-Hui Choi, Seung Kim
doaj   +1 more source

Plasmatic and cell-based enhancement by microparticles originated from platelets and endothelial cells under simulated in vitro conditions of a dilutional coagulopathy

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background Aggressive fluid management and other external factors may lead to hypothermia, acidosis and hemodilution (defined as Lethal Triad, LT) contributing to a trauma-induced coagulopathy (TIC) that worsens patients’ outcomes.
Julia K. Böhm, Nadine Schäfer, Marc Maegele, Birgit Stümpges, Ursula Bauerfeind, Michael Caspers   +5 more
doaj   +1 more source

THE REGULATORY ROLE OF COAGULATION FACTORS ON ARTERIAL FUNCTION

Artery Research, 2018
The coagulation takes place in the physiological system of hemostasis. Hemostasis is known to be disturbed in many diseases leading to hemorrhages or thrombosis.
Jeremy Lagrange
doaj   +1 more source

Responses of some blood coagulation factors in recovery period after interval and continuous efforts for swimmers [PDF]

مجلة الرافدين للعلوم الرياضية, 2012
تحددت مشكلة البحث في دراسة استجابات بعض عوامل تخثر الدم في فترة استعادة الشفاء بعد الجهدين الفتري والمستمر لدى السباحين. وهدف البحث إلى الكشف عن استجابات بعض عوامل تخثر الدم في فترة الاستشفاء بعد الجهد الفتري والمستمر وفي فترة الاستشفاء(1) ساعة بعد ...
Nashwan I. Abdullah
doaj   +1 more source

Blood coagulation factor VIII: An overview

Journal of Biosciences, 2003
Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be ...
G M, Bhopale, R K, Nanda
openaire   +2 more sources

Fluorescence artifact correction in the thrombin generation assay: Necessity for correction algorithms in procoagulant samples

Research and Practice in Thrombosis and Haemostasis, 2021
Introduction The thrombin generation (TG) test is a global hemostasis assay sensitive to procoagulant conditions. However, some TG assays may underestimate elevated TG when the thrombin fluorogenic substrate is depleted or fluorescence is attenuated by ...
William C. Chang, Joseph W. Jackson, Kellie R. Machlus, Alisa S. Wolberg, Mikhail V. Ovanesov   +4 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Management of a Patient with Bombay Blood Group and Chronic Liver Disease with Subdural Hematoma

Journal of Neuroanaesthesiology and Critical Care, 2022
The Bombay blood group is an extremely rare entity within the conventional ABO blood grouping system. End-stage liver disease also presents with myriad disorders of coagulation due to impaired synthesis and dysfunction of clotting factors, which ...
Siddharth Chavali, Subodh Raju, Suresh Kanasani, Abhirama C. Gabbita   +3 more
doaj   +1 more source