Results 91 to 100 of about 872,383 (328)

Effects of Prestorage Leukoreduction on the Rate of Febrile Nonhemolytic Transfusion Reactions to Red Blood Cells in a Tertiary Care Hospital

open access: yesAnnals of Medical and Health Sciences Research, 2015
Background: Febrile nonhemolytic transfusion reactions (FNHTRs) are relatively common complications associated with allogenic transfusion. White blood cells (WBCs or leukocytes) are considered to be an important cause of FNHTRs; the rate of WBC derived ...
K. Rajesh, S. Harsh, K. Amarjit
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Complex Web of Othernesses in Marcus Gardley’s Play The Road Weeps, the Well Runs Dry

open access: yesSocieties, 2018
Marcus Gardley’s play The Road Weeps, the Well Runs Dry (2013) traces the development of a Black Seminole community in the Indian Territory from 1850 to 1866, with occasional flashbacks to the days of the Seminoles’ removal from Florida ...
Claus-Peter Neumann
doaj   +1 more source

Evidence that host size determines liver size: Studies in dogs receiving orthotopic liver transplants [PDF]

open access: yes, 1987
Orthotopic liver transplantation was performed in two groups of dogs; Group I animals consisted of large dogs that served as recipients of livers obtained from smaller dogs while Group II animals consisted of dogs that received liver from donor dogs of ...
Bucher   +28 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

THE CONSTRUCTION OF PHYSICAL REHABILITATION PROGRAMS IN THE PREOPERATIVE PERIOD FOR PATIENTS THAT WILL REMOVE OF INTERVERTEBRAL DISC’ PROLAPSE IN THE LUMBAR SPINE

open access: yesPedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2014
The ineffectiveness of conservative treatment will make the need for surgery in 4-5% of patients suffering from low back pain with hernias of the lumbar and sacral spine.
E.B. Lazarieva   +3 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

POLYMYXIN-SEWN HEMOSORBENT FOR THE TREATMENT OF PATIENTS WITH SEPTIC SHOCK

open access: yesНеотложная медицинская помощь, 2016
. The key component of the sepsis pathogenesis is the gram-negative bacteria endotoxin. It is a lipopolysaccharide of the bacterial wall, which circulation in the bloodstream results in unlimited activation of some biological systems, causing serious ...
V. V. Kirkovsky   +3 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

STUDY OF MICROCIRCULATION OF THE EYEBALL IN THE SURGICAL TREATMENT OF INTRAOCULAR HEMORRHAGE

open access: yesКубанский научный медицинский вестник, 2014
This article describes changes in the microcirculation of the eyeball in patients with hemophthalmus during vitrectomy. We examined 24 patients who underwent vitrectomy, according to testimory local lasercoagulation of retinal vessels.
A. V. Malyshev   +6 more
doaj  

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