Results 81 to 90 of about 7,074,857 (310)

A CASE OF MYCOTIC SEPSIS DUE TO TRICHOSPORON COREMIIFORME IN A TRAUMA PATIENT IN MHAT-SHUMEN

Problems of Infectious and Parasitic Diseases
Trichosporon spp. are yeast-like fungi,a rare cause of mycotic sepsis. We share a case report of a thirty-three year old man with polytrauma after a car accident, who died after a long hospitalization and treatment in intensive care unit.
Stanislava Voycheva, Emilia Bozova, Ivva Philipova, Lyubomira Boyanova   +3 more
doaj   +1 more source

Blood culture contamination rates at different level healthcare institutions in the Western Cape, South Africa

Southern African Journal of Infectious Diseases, 2020
Sterile blood culture (BC) collection procedures are important to prevent the consequences of contamination, namely, prolonged patient hospitalisation, unnecessary antimicrobial exposure and an increase in hospital costs.
Christoffel J. Opperman, Banyana Baloyi, Sipho Dlamini, Nazlee Samodien   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Antimicrobial Resistance in Hospital-acquired Bloodstream Infections among Children in a Pediatric Hospital in Bolivia

Journal of Global Infectious Diseases
Introduction: Antimicrobial resistance (AMR) is a growing threat to global public health. In hospitals, infant mortality due to bacterial sepsis is associated with AMR.
Diana Rodriguez, Shirley Equilia, Cristian Roca, Erica Ludi, Grover Espada, Zulma García, Blanca Machuca, Taryn Clark, Robert H. Gilman   +8 more
doaj   +1 more source

Limited utility of blood cultures in the management of febrile outpatient kidney transplant recipients

Journal of Microbiology, Immunology and Infection, 2017
Background/Purpose: Blood cultures for patients suspected of having bacteremia are standard practice, although several studies demonstrate that blood cultures have limited utility because of a low true-positive rate and infrequent resultant changes in ...
Kazuaki Tokodai, Noritoshi Amada, Izumi Haga, Atsushi Nakamura, Toshiaki Kashiwadate, Naoki kawagishi, Noriaki Ohuchi   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Diagnosis of brucellosis by use of BACTEC blood culture and confirmation by PCR [PDF]

Brucellosis is one of the most common zoonotic diseases in Iran. Growth of Brucella is slow and blood cultures of these bacteria are time-consuming via classical methods.
مالک نژاد, پرویز, پیری دوگاهه, هادی, جعفری, سیروس, امیرزرگر, علی اکبر, فتح اله زاده, بهرام   +4 more
core  

Surveillance of HIV-1 genetic subtypes and diversity in the US blood supply

, 2000
BACKGROUND: Recent reports of variant (non-subtype B) HIV infections in US populations have raised concerns about the sensitivity of subtype B virus-based donor screening and diagnostic assays.
Finlayson, T., Gwinn, M., Busch, M. P., Sullivan, M. T., Oliveira, C. F. de, Machado, D. M., Kessler, D., Lackritz, E. M., Operskalski, E. A., Williams, A. E., Mosley, J. W., Diaz, R. S.   +11 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source