Results 31 to 40 of about 1,717,611 (352)
Red blood cell (RBC) transfusion is one of the most frequently performed clinical procedures and therapies to improve tissue oxygen delivery in hospitalized patients worldwide.
Hong-Yang Li, Kai Guo
semanticscholar +1 more source
Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. [PDF]
There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these
Atkinson, Mark A+6 more
core +2 more sources
ABO blood group and COVID‐19: a review on behalf of the ISBT COVID‐19 Working Group
Growing evidence suggests that ABO blood group may play a role in the immunopathogenesis of SARS‐CoV‐2 infection, with group O individuals less likely to test positive and group A conferring a higher susceptibility to infection and propensity to severe ...
R. Goel+23 more
semanticscholar +1 more source
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens
Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and
Bishal Singh, M. Leuthold, G. Hansman
semanticscholar +1 more source
The dendritic cell-specific intracellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is an important receptor of the immune system. Besides its role as pathogen recognition receptor (PRR), it also interacts with endogenous glycoproteins through ...
Pablo Valverde+9 more
semanticscholar +1 more source
The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A
Key Points The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2.
Shang-Chuen Wu+8 more
semanticscholar +1 more source
Identification of the Kna/Knb polymorphism and a method for Knops genotyping [PDF]
BACKGROUND: DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)—a ligand for rosetting of Plasmodium falciparum-infected RBCs.
Daniels+17 more
core +1 more source
INTRODUCTION Rhesus (Rh) antigen was discovered in 1940 by Karl Landsteiner and Wiener. Due to its immunogenicity along with A, B antigens, Rh D antigen testing was made mandatory in pre-transfusion testing.
D. Gundrajukuppam+3 more
semanticscholar +1 more source
QuilA-adjuvanted T. gondii lysate antigens trigger robust antibody and IFNγ+ T cell responses in pigs leading to reduction in parasite DNA in tissues upon challenge infection [PDF]
Toxoplasma gondii is an intracellular parasite of all mammals and birds, responsible for toxoplasmosis. In healthy individuals T. gondii infections mostly remain asymptomatic, however this parasite causes severe morbidity and mortality in ...
Cox, Eric+6 more
core +2 more sources
INTRODUCTION The ABO blood group system was the significant element for forensic serological examination of blood and body fluids in the past before the wide adaptation of DNA typing.
R. Metgud+3 more
semanticscholar +1 more source