Results 41 to 50 of about 1,751,271 (390)

The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A

Blood Advances, 2021
Key Points The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2.
Shang-Chuen Wu, C. Arthur, Jianmei Wang, H. Verkerke, C. Josephson, D. Kalman, J. Roback, R. Cummings, S. Stowell   +8 more
semanticscholar   +1 more source

Molecular Insights into DC-SIGN Binding to Self-Antigens: The Interaction with the Blood Group A/B Antigens

ACS Chemical Biology, 2019
The dendritic cell-specific intracellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is an important receptor of the immune system. Besides its role as pathogen recognition receptor (PRR), it also interacts with endogenous glycoproteins through ...
Pablo Valverde, S. Delgado, J. D. Martínez, J. Vendeville, J. Malassis, B. Linclau, N. Reichardt, F. Cañada, J. Jiménez‐Barbero, A. Ardá   +9 more
semanticscholar   +1 more source

Blood group antigens and malaria susceptibility

Frontiers in Cellular and Infection Microbiology
Blood-group antigens are increasingly recognized as key modulators of malaria susceptibility. This review synthesizes current evidence on how erythrocyte surface molecules shape parasite invasion, cytoadherence, immune evasion, and disease severity.
Fang-Fang Liu, Jing Liang, Ming Gao, Ke Li   +3 more
doaj   +1 more source

Expressivity of ABO antigens and increased predisposition for periodontal disease: A cross-sectional analysis

Journal of the Scientific Society, 2021
Context and Aim: Association between certain systemic diseases and ABO antigens is a well-known fact. The purpose of this study was to determine whether there is any association between periodontal disease and ABO blood group antigens.
J Suresh Babu, C Swarnalatha, Tayf Naif Radhi Alshammari, Farahnaz Muddebihal, Manisha B Patil, Deepak R Kolte, Mohammad Saafaq Alshammari, Fatma Ayyad Alshammari, Abhishek Singh Nayyar   +8 more
doaj   +1 more source

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. [PDF]

, 2019
There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these
Atkinson, Mark A, Dang, Hoa, Kaufman, Daniel L, Sun, Ren, Tian, Jide, Wu, Ting-Ting, Yong, Jing   +6 more
core   +2 more sources

Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes [PDF]

, 2012
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the
AB Fredriksen, AB Pedersen, AE O'Connell, AE Schwab, B de Andres, B Manoury, BL Makepeace, BW Li, C Klotz, C Martin, C Martin, D Abraham, D Abraham, D Horst, D Knox, David W. Taylor, DH Barouch, DL Redmond, E Maraskovsky, G Ahlen, G Nchinda, GT Joseph, HA Farid, HongLin Luo, J Gardon, J Murray, JE Allen, JE Allen, JJ Donnelly, JP Hewitson, Judith E. Allen, KJ Fairlie-Clarke, KJ Ishii, LM Mir, LM Mir, LvG Jørgensen, MD Taylor, MD Taylor, MY Osei-Atweneboana, N Gomez-Escobar, Nick Gray, O Golden, PJ Hotez, R Ihaka, RM Maizels, RT Rwegoshora, S Babayan, S Frontier, S Mendez, S Ramachandran, S Thirugnanam, SA Babayan, SA Babayan, SB Anand, SB Anand, SB Anand, Simon A. Babayan, SM Sumida, Stephen John Davies, W Harnett, WF Gregory, WF Gregory, Y Dash, Y Wu   +63 more
core   +8 more sources

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures

Frontiers in Chemistry, 2022
Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance the
Julia König-Beihammer, Ulrike Vavra, Yun-Ji Shin, Christiane Veit, Clemens Grünwald-Gruber, Yasmin Gillitschka, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Dieter Mitteregger, Andreas Weinhäusel, Richard Strasser   +11 more
doaj   +1 more source

Evaluation of the Secretor Status of ABO Blood Group Antigens in Saliva among Southern Rajasthan Population Using Absorption Inhibition Method.

Journal of clinical and diagnostic research : JCDR, 2016
INTRODUCTION The ABO blood group system was the significant element for forensic serological examination of blood and body fluids in the past before the wide adaptation of DNA typing.
R. Metgud, Nidhi Khajuria, Mamta, G. Ramesh   +3 more
semanticscholar   +1 more source

Glycophorins and the MNS blood group system: a narrative review

Annals of Blood, 2021
The MNS blood group system, International Society of Blood Transfusion (ISBT) 002, is second after the ABO system. GYPA and GYPB genes encode MNS blood group antigens carried on glycophorin A (GPA), glycophorin B (GPB), or on variant glycophorins.
G. Lopez, C. Hyland, R. Flower
semanticscholar   +1 more source

Extended phenotyping of blood group antigens: Towards improved transfusion practices

Global Journal of Transfusion Medicine, 2020
Even though the International Society of Blood Transfusion has defined 38 blood group systems, only ABO and RhD are matched while selecting a compatible unit for blood recipients of Indian origin.
Swati Kulkarni, Harita Maru
doaj   +1 more source