Results 51 to 60 of about 1,751,271 (390)

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Revisiting the role of histo-blood group antigens in rotavirus host-cell invasion

Nature Communications, 2015
Histo-blood group antigens (HBGAs) have been proposed as rotavirus receptors. H type-1 and Lewisb antigens have been reported to bind VP8* from major human rotavirus genotypes P[4], P[6] and P[8], while VP8* from a rarer P[14] rotavirus recognizes A-type
Raphael Böhm, F. Fleming, A. Maggioni, V. Dang, G. Holloway, B. Coulson, M. von Itzstein, T. Haselhorst   +7 more
semanticscholar   +1 more source

QuilA-adjuvanted T. gondii lysate antigens trigger robust antibody and IFNγ+ T cell responses in pigs leading to reduction in parasite DNA in tissues upon challenge infection [PDF]

, 2019
Toxoplasma gondii is an intracellular parasite of all mammals and birds, responsible for toxoplasmosis. In healthy individuals T. gondii infections mostly remain asymptomatic, however this parasite causes severe morbidity and mortality in ...
Cox, Eric, Devriendt, Bert, Dierick, Katelijne, Dorny, Pierre, Gisbert Algaba, Ignacio, Rahman, Mizanur, Verhaegen, Bavo   +6 more
core   +2 more sources

A Scenario for the Origin of Blood Group Antigens [PDF]

West Indian Medical Journal, 2014
A long time ago, in the unpublished manuscript of a book on evolutionary biology, I put forward a hypothesis for the origin of blood group antigens that correlates with recent medical findings in relation to the ABO blood group system. My scenario is based upon interactions between invading organisms (whether viral, bacterial, protozoan, or multi ...
openaire   +2 more sources

Genetic Analysis of ABO and Rh Blood Groups in Brahmin Population of Uttar Pradesh, India” [PDF]

, 2011
A series of glycoprotein and glycolipids on the red blood cell surface constitute blood group antigens. These are A, B, AB and O in ABO blood group system and Rh in rhesus blood group system. These antigens are genetically controlled.
Vandana V. Rai
core   +1 more source

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]

, 2015
BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M, Cockburn, Ian, Nganou-Makamdop, Krystelle, Sauerwein, Robert W, van Gemert, Geert-Jan, Zavala, Fidel   +5 more
core   +2 more sources

Blood group antigen distribution in Lao blood donors [PDF]

Immunohematology, 2012
Abstract Blood group antigens can be distributed differently within different nationalities. Therefore, information about the prevalence of blood group antigens in the Lao population will be useful for providing better blood transfusion services in the Lao People’s Democratic Republic.
C, Keokhamphoui, Y, Urwijitaroon, D, Kongphaly, T, Thammavong   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phenotypic Frequency of Clinically Significant Blood Group Antigens (Rh, Kell, Kidd, and Duffy) in Blood Donors of the Blood Center at a Tertiary Care Referral Teaching Hospital in Tirupati, Andhra Pradesh, South India

Global Journal of Transfusion Medicine
Background and Objectives: The knowledge of various blood group antigen and phenotype frequencies in a population is important in selecting compatible blood in alloimmunized patients. Such information in Indian population is very limited.
K. V. Sreedhar Babu, M. D. Praveen, B. Suresh Babu   +2 more
doaj   +1 more source